22 citations
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June 2005 in “Clinical Oncology” This case report documents an instance of symptomatic hypothyroidism developing in a patient with papillary thyroid carcinoma after beginning treatment with orlistat.
4 citations
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January 2018 in “JBRA assisted reproduction” This study found that orlistat significantly reduced weight and total testosterone levels in Iranian women with polycystic ovary syndrome after 12 weeks of treatment.
32 citations
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January 2006 in “Liver transplantation” This case report describes a 60-year-old male with vitamin A toxicity leading to severe liver disease and symptoms that resolved following liver transplantation, suggesting transplantation as a treatment option for noncirrhotic portal hypertension when symptoms do not improve after stopping vitamin A.
October 2025 in “The American Journal of Gastroenterology” In this case report, acute liver failure was attributed to a 34-year-old woman's high-dose zinc supplementation taken for three weeks, illustrating that even commonly used supplements can lead to serious conditions like liver failure.
January 2026 in “Nutrición Hospitalaria” In this study, researchers identified significant signals indicating previously unrecognized risks of lipid metabolism abnormalities for several drugs, urging the need for better monitoring and label updates.