11 citations
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September 2020 in “Steroids” This study developed a new method using liquid chromatography-tandem mass spectrometry to measure multiple steroid hormones in hair, requiring significantly fewer strands than previous methods, with high accuracy and precision.
11 citations
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January 2006 in “Analytica Chimica Acta” Validated method reliably measures finasteride in tablets using liquid chromatography.
This study found that liquid nitrogen cryotherapy resulted in good responses in 33% of patients with recalcitrant alopecia areata, although nearly 30% showed no response.
58 citations
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December 2012 in “Aaps Pharmscitech” This study suggests that finasteride-loaded liquid crystalline nanoparticles could be a viable alternative to oral administration for treating androgenetic alopecia due to their controlled release and skin permeation properties.
51 citations
,
February 2010 in “Analytical and Bioanalytical Chemistry” Researchers developed a method to detect hormone-blocking drugs in wastewater and found them in Beijing's sewage, suggesting they can survive sewage treatment.
49 citations
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December 2017 in “Journal of pharmaceutical and biomedical analysis” This study developed and validated a high-resolution mass spectrometry method to screen for prohibited substances and analyze six endogenous steroids in urine according to World Antidoping Agency requirements, demonstrating its effectiveness for antidoping analysis.
47 citations
,
September 2013 in “Aaps Pharmscitech” This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.
38 citations
,
June 2005 in “Contact Dermatitis” This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.
32 citations
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June 2017 in “Journal of Pharmaceutical Sciences” This study found that coating liquid crystalline nanoparticles with chitosan significantly enhanced the skin permeation of 5α-reductase inhibitors, suggesting a promising strategy for improving topical delivery in androgenetic alopecia treatment.
26 citations
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June 2011 in “International Journal of Pharmaceutics” This study found that solid lipid nanoparticles with minoxidil were as effective as commercial solutions for skin penetration and were non-corrosive, indicating potential for hair loss treatment.
17 citations
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August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.
16 citations
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August 2014 in “Archives of Pharmacal Research” This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.
15 citations
,
November 2006 in “Journal of Pharmaceutical and Biomedical Analysis” This study developed and validated a reliable method to measure finasteride levels in human plasma, which was successfully used to assess its pharmacokinetics after a 5 mg dose in healthy volunteers.
14 citations
,
September 1954 in “Textile Research Journal” This study found that hair absorbs significant amounts of NaBr from solution, with absorption increasing linearly with solution concentration and additional effects noted with acidic or basic solutions.
11 citations
,
January 2006 in “Drug development and industrial pharmacy” In this study, adding TPGS to a minoxidil formulation improved local retention and reduced systemic absorption in certain solvent mixes, particularly with a balance of alcohol and PEG 400.
10 citations
,
January 2019 in “Journal of Chromatography B” This study used a newly validated method to find that one-year finasteride treatment resulted in no significant differences in urinary androgen and prostaglandin levels between male pattern baldness patients and normal controls.
6 citations
,
March 2018 in “Journal of Chromatography A” This study describes an analytical technique combining field-enhanced sample stacking with dispersive liquid-liquid microextraction, offering improved sensitivity for detecting finasteride and its metabolite in urine samples from patients treated for androgenetic alopecia.
5 citations
,
October 2018 in “Journal of Clinical Laboratory Analysis” This study found that improved testosterone measurement using LC-MS/MS in women with PCOS revealed a stronger correlation between hyperandrogenism and insulin resistance than previously detected.
2 citations
,
October 2010 in “European Journal of Drug Metabolism and Pharmacokinetics” Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
December 2023 in “International Journal of Advanced Research in Science, Communication and Technology” This study developed and validated a precise and rapid HPLC method to simultaneously determine Minoxidil and Finasteride in pharmaceuticals, demonstrating successful application for routine quality control without interference from excipients.
December 2022 in “Deleted Journal” In this study, topical application of keratin extract from wool promoted hair growth in mice by reducing the time for initiation and completion of growth phases and improving hair quality.
March 2022 in “VNU Journal of Science Medical and Pharmaceutical Sciences” This study developed a sensitive method using LC-ESI-MS/MS for accurate and reliable measurement of nine steroid hormones in children's serum.
February 2020 in “Drug Analytical Research” This study found that magistral topical minoxidil solutions had differences in color, viscosity, and acidity compared to industrial formulations and issues with drug content and dosage indication, despite similar follicular penetration.
September 2018 in “Cosmetics” This study found that anisotropic osmolyte solutions may improve hair follicle turnover and condition in both in vitro and in silico models, as well as in human volunteers with hair disorders.
April 2016 in “Annals of laboratory medicine” The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.
December 2023 in “Kiểm nghiệm và An toàn thực phẩm/Kiểm nghiệm và An toàn thực phẩm (online)” This study developed a liquid chromatography with tandem mass spectrometry method to detect sex hormones in health supplements from Hanoi, Vietnam, finding three out of 16 samples contained sex hormones, including banned testosterone at low levels (~0.5 mg/kg).
January 2019 in “Arabian Journal of Chemistry” This study developed and validated an HPLC method to quantify impurities in finasteride, demonstrating its suitability for quality assurance of the drug and its related substances.
February 2024 in “International Journal For Multidisciplinary Research” This study introduced a unique herbal hair oil formulation that combines natural extracts such as coconut oil, sesame seeds, and hibiscus to hydrate the scalp, stimulate hair follicles, and improve overall hair appearance, aiming to address issues like thinning, dryness, and dandruff.
45 citations
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June 2008 in “Journal of pharmaceutical and biomedical analysis” This study developed a new HPLC method for detecting prohibited substances like minoxidil and hydrocortisone in cosmetic products, achieving high sensitivity and successful application to real-world samples.
12 citations
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October 1954 in “Textile Research Journal” This study found that alkali bromide solutions are absorbed into hair depending on salt activity, and the presence of the salt increases water absorption compared to normal conditions.