TLDR Magistral pharmacies had issues with production quality and dosage accuracy.
The study evaluated the quality of magistral minoxidil topical solutions (A, B, and C) compared to an industrial formulation. Differences were found in color, viscosity, and pH, with magistral solutions being more acidic. Density varied with ethanol content, and only the industrial and magistral sample C met the expected drug content (90-110%). Dosages from magistral pharmacies were significantly lower than industrial recommendations. All solutions showed similar follicular penetration of minoxidil. The study concluded that magistral pharmacies had issues with production quality and dosage accuracy.
40 citations,
January 2018 in “Pharmaceutics” Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.
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April 2017 in “Journal of The American Academy of Dermatology” Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
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January 2015 in “International Journal of Biological Macromolecules” Chitosan nanoparticles improve minoxidil delivery to hair follicles for better alopecia treatment.
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December 2013 in “Drug Delivery and Translational Research” Niosomes improve minoxidil skin penetration for hair loss treatment.
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
