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Glossary pH

measures acidity or alkalinity of a substance on a scale

pH is a measure of how acidic or basic a substance is, on a scale from 0 to 14. A pH of 7 is considered neutral, while values below 7 indicate acidity and values above 7 indicate alkalinity. In the context of hair and scalp health, maintaining a balanced pH (around 4.5 to 5.5) is crucial for preventing issues like dryness, irritation, and microbial growth.

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Clinics

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Research

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research Mechanisms and applications of the anti-inflammatory effects of photobiomodulation

520 citations , January 2017 in “AIMS biophysics”

This review discusses the effects of photobiomodulation, particularly its potential to reduce inflammation in various conditions, but it does not report new clinical findings.

research Engineering Robust Ag‐Decorated Polydopamine Nano‐Photothermal Platforms to Combat Bacterial Infection and Prompt Wound Healing

513 citations , February 2022 in “Advanced Science”

This study demonstrated that incorporating PDA@Ag nanoparticles into a cationic guar gum hydrogel significantly enhanced photothermal conversion efficiency, achieving superior antibacterial efficacy both in vitro and in vivo, advancing the potential of PDA as a photothermal antibacterial agent.

research Pharmacology of anabolic steroids

441 citations , May 2008 in “British Journal of Pharmacology”

This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.

research Low-Level Light/Laser Therapy Versus Photobiomodulation Therapy

433 citations , April 2015 in “Photomedicine and laser surgery”

This editorial discusses the terminology and distinctions between Low-Level Light/Laser Therapy and Photobiomodulation Therapy but reports no new clinical findings.

research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance

403 citations , December 2018 in “Cell stem cell”

This study suggests that phenotypic plasticity, including processes like dedifferentiation and transdifferentiation, plays a crucial role in cancer initiation, progression, and therapy resistance, broadening our understanding of cancer dynamics and potential treatment strategies.

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Community Join

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community Phase 3 for PP405 will now start in 2027

in Chat 81 upvotes 1 month ago

Phase 3 for PP405 will start in 2027, disappointing many who expected it this year. Some users are trying treatments like topical minoxidil and topical dutasteride while waiting for new developments.

community Phase 2B trial for PP405 leaked (The study Pelage DOESN'T want you to see)

5 months ago

The conversation discusses hair loss treatments, mentioning minoxidil, finasteride, RU58841, VDPHL, GT20029, and follicle cloning as potential solutions. It also reveals that the discussion about PP405 was an April Fool's joke.

community Phase II topical dut study - outperforms oral fin with a minor DHT reduction

in Research/Science 61 upvotes 7 months ago

Topical dutasteride 0.05% is more effective for hair growth than oral finasteride 1mg, with minimal DHT reduction. The formulation uses castor oil and MCTs for better absorption but is not widely available until 2028.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

2 upvotes 1 year ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Photo results of oral min have many got growth from it

in Progress Pictures 1 upvotes 1 year ago

The user is seeking before-and-after photos of hair growth results from using oral or topical Minoxidil, as they couldn't use Finasteride but are using RU58841. They are curious about the effectiveness of Minoxidil alone.

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Learn

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learn phenoxyethanol

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learn KX-826

Kintor Pharmaceutical: KX-826, a New Name in Hair Loss Research KX-826 (pyrilutamide) is an experimental topical androgen receptor blocker from Kintor Pharmaceutical. It is not approved as a medicine anywhere; the company reports that its China Phase III trial met its primary endpoint at 24 weeks, but the trial data has been released through corporate announcements rather than peer-reviewed journals and long-term safety is unknown.

learn Scalp Micropigmentation

Can I see before-and-after photos of scalp micropigmentation? Yes, many providers offer before-and-after photos during consultations.

learn Hair Transplant

Can I see before-and-after photos of previous hair transplant patients? Yes, most clinics provide before-and-after photos of previous hair transplant patients.

learn Ketoconazole

Is it better to buy a ketoconazole shampoo from a pharmacy or a brand name one? Approved generic and brand-name ketoconazole shampoos carry the same active ingredient at the same strength, and regulators require a generic to be shown equivalent to the product it copies; no published head-to-head trial compares them, and generics are usually the cheaper option.

learn Finasteride

Finasteride Results Timeline: How Long It Takes to Work, Shedding Phases, and Expected Outcomes Trial data and community reports both put the first visible changes on finasteride at roughly 3 to 6 months, with the clearest results between 6 and 12 months; an early shedding phase is common and usually temporary. The benefit lasts only while the drug is taken, and it is prescription-only.

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