21 citations
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January 2017 in “Skin Pharmacology and Physiology” In this noninferiority study, researchers found that a 0.2% caffeine-based topical liquid was not less effective than 5% minoxidil solution in improving hair growth in men with androgenetic alopecia over six months.
September 2024 in “Journal of the American Academy of Dermatology” This study found that a new compounded topical solution for alopecia was clinically tolerable and did not cause irritation, while also showing potential to enhance hair growth through fibroblast proliferation and gene expression.
January 2015 in “CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION)” This study developed a rapid and reliable ultra high performance liquid chromatography method for analyzing 17 key ingredients in hair growth cosmetics.
4 citations
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January 2011 in “Analytical Letters” This study demonstrated that a flow injection method using potassium permanganate for detecting minoxidil provided accurate recoveries and agreed closely with HPLC results, showing potential for effective analysis of commercial samples.
1 citations
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October 2020 in “Annales pharmaceutiques françaises” In this study, researchers developed and validated a rapid and robust chromatographic method to assess the concentration of Minoxidil and Finasteride in a new topical formulation for alopecia, demonstrating its ability to distinguish between different types of formulations using in vitro diffusion data.
In this study, researchers assessed the physical-chemical and microbiological stability of various pharmaceutical ingredients in the vehicle TrichoSolTM, finding differing beyond-use dates for the compounds, such as 180 days for cetirizine hydrochloride, but only 90 days for progesterone at higher concentrations.
December 2024 in “Skin Appendage Disorders” Researchers reviewed 13 clinical trials on non-prescription monotherapies like procyanidin and cetirizine for androgenetic alopecia, finding potential improvements in hair density and diameter, but emphasized the need for more robust trials to confirm efficacy and safety.
February 2024 in “Trends in Sciences” This study examined the stability of two 5α-reductase inhibitors in Tectona grandis extracts, finding that they are more stable in acidic environments and degrade rapidly under heat and light unless protected, suggesting the need for careful storage when developing anti-hair loss medications.
March 2026 in “Journal of medical & health sciences review.” In this study, both 5% minoxidil foam and 5% minoxidil liquid solution effectively improved hair diameter and density in male patients with androgenetic alopecia over 12 weeks, with the foam formulation showing a slight advantage in patient satisfaction and hair density gain.
127 citations
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June 2006 in “International Journal of Pharmaceutics” This research found that liquid-state liposomes and niosomes may enhance finasteride delivery to pilosebaceous units in hamsters more effectively than gel-state vesicles or hydroalcoholic solution.
3 citations
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March 2005 in “Iranian Journal of Pharmaceutical Sciences” This study demonstrated that liquid-state vesicles may reduce the absorption of finasteride through the skin while increasing its concentration and retention in the dermis layer in hamster models.
8 citations
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June 2017 in “JAMA Dermatology” Women pay more for the same 5% minoxidil foam than men, but prices for liquid solutions are similar.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This guide explores the fundamental science and practical applications of nanocrystal technologies to enhance the bioavailability of poorly water-soluble drugs, detailing synthesis methods, stability solutions, and drug delivery innovations like hydrogel composites and microneedle platforms.
1 citations
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August 1978 in “Dicp-The annals of pharmacotherapy” A liquid protein diet caused hair loss in a young woman.
1 citations
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February 2002 in “Dermatologic Surgery” A cheap stainless steel container from a retail store can store liquid nitrogen effectively for 8-12 hours, saving money for medical practitioners.
February 2002 in “Dermatologic Surgery” A cheap stainless steel container from a retail store can store liquid nitrogen effectively for 8-12 hours, offering a cost-effective alternative to specialized medical containers.
February 2024 in “PubMed” This study reported that minoxidil lotions produced using a propylene glycol-free base, Aloplus Total, demonstrated high minoxidil solubility and maintained chemical and physical stability for over 180 days, suggesting suitability for enhanced topical treatments of androgenetic alopecia.
September 2024 in “Research Repository Universitas Islam Negeri Maulana Malik Ibrahim (University of Southampton)” In this study, researchers identified an optimal shampoo formulation using Design Expert software, which showed no significant differences in viscosity and foam height, and the physical characteristics met acceptable standards, suggesting its potential for supporting hair health and preventing hair loss.
5 citations
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January 2014 in “Asian Journal of Chemistry” This study developed a simple and cost-effective chromatographic method for simultaneously analyzing betamethasone dipropionate and calcipotriol, achieving rapid separation within 7 minutes suitable for routine applications.
This study evaluated the stability of multiple active ingredients in TrichoSol™ for use in alopecia treatments, finding varying stability durations at room temperature—up to 180 days for some ingredients—supporting its use as a compounding vehicle in personalized therapies.
1 citations
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October 2015 in “The Pharma Innovation Journal” This study found that the optimal method to introduce Saw Palmetto extract into emulsion bases for androgenic alopecia treatment involves mixing it with 48% ethanol at the end of the formulation process.
July 1988 in “Journal of The American Academy of Dermatology” This article reviews therapeutic advances published between December 1986 and December 1987 but reports no new research findings; readers are advised to consult the original articles before considering new therapies.
13 citations
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January 1995 in “Journal of the American Institute for Conservation” This study introduced a new method for extracting red mordant dyes from wool fibers that preserved the fibers for further analysis and allowed for spectrophotometric examination of the dyes' absorption curves.
January 2025 in “Journal of Medicinal Food” This abstract mentions that while synthetic drugs like minoxidil and finasteride for androgenic alopecia have side effects, the characteristics of popular natural alternatives, such as soybean, remain largely unreported, despite consumer preference for these products.
4 citations
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June 2013 in “PubMed” This study found that minoxidil in Espumil Foam Base remains stable for at least 90 days when stored at room temperature and protected from light.
1 citations
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March 2019 in “Journal of AOAC INTERNATIONAL” New method quickly and accurately measures dexpanthenol in hair products.
11 citations
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September 2010 in “PubMed” In this study, the researchers compared the pharmacokinetics and tissue distribution of dihydroartemisinin in nanostructured lipid carriers versus in solution, finding longer mean residence times and variable organ accumulation with the nanostructured lipid carriers.
38 citations
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January 2012 in “Annales de Toxicologie Analytique” This study found that among bodybuilder-intended drugs from the black market, 33.8% of labeled products and 52.5% of steroidal oily solutions contained ingredients not matching their labels.
November 2025 in “Communications Materials” This research demonstrated that transforming pomelo peel into expanded sponges and carbonized aerogels can accelerate hemostasis and enhance healing in diabetic wounds while eradicating bacterial biofilms, offering an eco-friendly solution for wound care from agricultural waste.
November 2023 in “Regenerative Biomaterials” This study developed a degradable and bioactive citrate-based polyurethane adhesive that achieves rapid and strong tissue adhesion, exhibiting improved bonding strength in wet environments, biocompatibility, biodegradability, and hemostatic properties, with potential to enhance wound healing by promoting angiogenesis.