Stability of Minoxidil in Espumil Foam Base

May 2013 in “ PubMed ”

Christine M Geiger, Bridget Sorenson, Paul A Whaley

minoxidil Espumil Foam Base hydroalcoholic compounding vehicle contact dermatitis high-performance liquid chromatography Rogaine HPLC

TLDR Minoxidil in Espumil foam stays stable for at least 90 days at room temperature.

The study aimed to determine the stability of minoxidil in Espumil Foam Base, a hydroalcoholic compounding vehicle designed to minimize greasiness, itching, burning, and contact dermatitis. Minoxidil was compounded into a 50-mg/mL solution and stored in a plastic foam-activating bottle at room temperature. Stability was assessed over 90 days using a validated high-performance liquid chromatography method. The results indicated that minoxidil remained stable for at least 90 days when stored at room temperature and protected from light.

View this study on pubmed.ncbi.nlm.nih.gov →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Study shows significant improvement in hair with topical minoxidil and oral Vitamin d compared to just topical minoxidil alone.

in Minoxidil 206 upvotes 3 days ago

Taking oral Vitamin D alongside topical minoxidil improves hair density more than using minoxidil alone. Users discuss Vitamin D dosages, potential benefits, and the importance of combining it with Vitamin K2.

community Studies on Minoxidil show an increase in hair count shortly after starting treatment

in Minoxidil 118 upvotes 5 days ago

Minoxidil can initially cause hair shedding but often leads to increased hair count over time, with some users experiencing noticeable improvements within weeks. Combining Minoxidil with Finasteride may enhance hair health, though individual results vary.

community Why is Minoxidil not enough for hair loss? (No fin)

in Minoxidil 57 upvotes 6 days ago

Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.

community How to ease off oral minoxidil?

in Minoxidil 1 upvotes 1 week ago

The user experienced heart palpitations after increasing their oral minoxidil dosage and starting a new topical minoxidil formulation. They wish to stop oral minoxidil for heart health and continue with topical minoxidil.

community Is there any true alternatives to minoxidil that doesn't effect heartrate?

in Minoxidil 1 upvotes 1 week ago

A user with slight hair thinning is seeking alternatives to minoxidil due to concerns about heart rate effects, despite using finasteride without issues. They are looking for options that don't affect the heart.

community Minoxidil doing wonders already

in Minoxidil 476 upvotes 1 week ago

Minoxidil and finasteride are effectively improving hair growth, with the user experiencing significant progress in less than two months using topical minoxidil and occasionally finasteride. The user also incorporates wild hair growth oil, tea tree oil, and dermastamping into their routine.

Related Research

1 / 1 results

research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

3 citations, January 2018

A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.