TLDR Validated method reliably measures finasteride in tablets using liquid chromatography.
This document describes a study that validated a method for determining the amount of finasteride in Dilaprost tablets using liquid chromatography. The method was found to be reliable and robust, with a linear calibration curve over a concentration range of 0.250-0.750 mg/mL. The study also investigated the stability of the finasteride tablet powder and standard, finding that they remained stable after standing for 48 hours. Overall, the method was deemed suitable for use in quality control of finasteride tablets.
1040 citations,
October 1992 in “The New England Journal of Medicine” Finasteride effectively treats BPH but may increase sexual dysfunction risk.
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August 1985 in “Endocrinology” Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.
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March 2018 in “Journal of Chromatography A” New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
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March 2007 in “Journal of Pharmaceutical and Biomedical Analysis” Method measures finasteride in plasma, suitable for pharmacokinetic studies.
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May 1991 in “Journal of Chromatography B: Biomedical Sciences and Applications” Reliable method detects finasteride in human plasma at low doses.