Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study revealed specific patterns and potential functions of long non-coding RNAs during the hair follicle cycle of yaks, offering insights into their sequence conservation between yaks and cashmere goats.

This review explores how androgen administration might help alleviate inflammation and mitochondrial impairment in traumatic brain injury but reports no new experimental findings, calling attention to the need for further investigation.

This study found that weakened anchorage of hair shafts, associated with the abnormal expression of 14-3-3σ, may contribute to alopecia in Er/+ mice.

This study found that WWOX deficiency in mice leads to impaired skin development, reduced epidermal thickness, and significant hypothermia due to disrupted cell proliferation and homeostasis.

This review discusses genetically-engineered mouse models for studying melanocytes and reports no new experimental findings; it emphasizes their potential to address unanswered questions in melanoma biology.

This study found that the distribution of desmogleins is associated with specific types of keratinization and hair anchorage, as well as hypotrichosis.

This study found that maize root hairs respond differently to cold stress based on severity, with mild cold allowing limited growth through adaptive remodeling, while severe cold causes more pronounced inhibition and prioritizes stress defense, affecting transcriptome and morphology.

This research review highlights the potential of exosome therapy to transform stroke treatment, reporting that in animal models, exosomes can reduce neuroinflammation, oxidative stress, and cell death, while promoting brain repair and regeneration. However, more evidence is needed before clinical applications in humans are established.

This review discusses the pharmacological activities and mechanisms of forsythiasides, highlighting their potential therapeutic value, but reports no new clinical results.

In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.

This review evaluated the potential of adipose-derived stem cells (ADSCs) for burn treatment, finding promising regenerative healing effects, though most findings are at early experimental stages primarily in animal models.

This review describes various in vitro and ex vivo hair follicle models used to study hair growth and regeneration and explores their potential for developing hair loss treatments, but it does not report new results.

This study investigated the physicochemical properties of polystyrene-b-poly(acrylic acid) nanovesicles coated with modified chitosans, finding that they can effectively control surface charge and potentially serve as drug delivery carriers with a 50.7% encapsulation efficiency for minoxidil.

This study found that modifying biphasic calcium phosphate/poly(methyl methacrylate) bone cement with human hair keratin improves its hydrophilicity, mechanical properties, and supports bone repair in rats, indicating potential for orthopedic applications.

This review synthesizes evidence on how RNA modifications affect wound healing, particularly in skin, bone, and corneal injuries, emphasizing potential therapeutic strategies for burns and trauma in relation to these cellular processes.

This review discusses metal-organic frameworks for treating diabetic infected wounds and related applications, reporting no new clinical results but highlighting challenges like biosafety and production for future research.

This study observed distinct plasma miRNA profiles in alopecia areata, identifying several miRNAs downregulated in both mild and severe forms; machine learning models demonstrated strong predictive accuracy, and kinase inhibitors were suggested as promising therapeutic targets based on pathway analysis.

This editorial from Advances in Clinical and Experimental Medicine analyzed and discussed selected author instruction guidelines, emphasizing the importance of fulfilling certain requirements before peer review, such as financial disclosures and quality of tables and figures, for maintaining ethical integrity and efficient publication processes.

This study identified a unique circulating microRNA signature associated with severe alopecia areata, distinguishing it from other inflammatory skin conditions and suggesting these miRNAs as non-invasive biomarkers for diagnosis and potential therapeutic targets.

A new method improves the isolation of hair follicle cells for better hair growth research.

This study found that toll-like receptor 9 plays a previously unrecognized role in sensing skin injury and influencing tissue repair and regeneration in adult mice by modulating γδT cell migration.

This study on male rats found that finasteride treatment led to the differential expression of several genes in the hypothalamus and hippocampus, hinting at potential links to observed side effects like depression, anxiety, and cognitive disturbances.

This study identified Th22 cells as key effectors in hair regeneration driven by thymosin beta 15, suggesting they could be potential targets for hair regrowth therapies.

This review discusses strategies for hair follicle regeneration using tissue engineering and reports no new clinical results; the authors highlight potential future directions for promoting hair neoformation.

This review examines the potential of stem cells and their derived products, such as exosomes and conditioned media, in improving burn wound healing but presents no new clinical data.

This study found that m6A-circHECA enhances the differentiation of stem cells into hair follicle lineages in cashmere goats by sequestering miR-449a-5p, boosting LEF1 gene expression, and activating the Wnt/β-catenin pathway.

This study reviewed recent literature and reported that although PRP products are recognized for benefits in dermatology, including wound care and hair growth, there remains a need for standardized protocols and consensus to enhance their acceptance in cosmetic dermatology.

This study found that exosome-incorporated human amniotic membrane scaffolds notably enhanced diabetic skin wound healing in mice, suggesting potential applications for ADSC-derived exosomes in clinical settings.

This study found that silibinin may promote hair growth by increasing proliferation and activating the AKT and Wnt/β-catenin signaling pathways in 3D cultured human dermal papilla spheroids.

This study found that deoxyshikonin promoted wound healing in diabetic mice, suggesting it may contribute to wound repair in patients with diabetes.