Biocompatible Exosomes Derived From Pinctada Martensii Mucus For Therapeutic Melanin Regulation Via α-MSH/NF-κB/MITF Pathway

    January 2025 in “ Regenerative Biomaterials ”
    Dandan Mo, Weihao Zheng, Zixin Gao … Sheng Xu
    Studysummary In this study, researchers found that exosomes derived from Pinctada martensii mucus can effectively inhibit melanin production in melanoma cells and zebrafish without adverse effects, potentially offering a promising therapeutic strategy for treating pigmentary disorders by modulating the NF-κB signaling pathway.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on academic.oup.com →
    Discuss this study in the Community →

    Research cited in this study 7

    1. Exosomes Derived From Mouse Vibrissa Dermal Papilla Cells Promote Hair Follicle Regeneration During Wound Healing By Activating Wnt/β-Catenin Signaling Pathway Journal of Nanobiotechnology · 2024
    2. NF-κB in Biology and Targeted Therapy: New Insights and Translational Implications Signal transduction and targeted therapy · 2024
    3. Peptide CyRL-QN15 Accelerates Hair Regeneration in Diabetic Mice Through Binding to the Frizzled-7 Receptor 动物学研究 · 2024
    4. Stem Cell-Derived Exosomes: Emerging Therapeutic Opportunities for Wound Healing Stem cell research & therapy · 2023
    5. Epimedium Brevicornum Maxim Extract Enhances Melanin Biosynthesis and Melanosome Biogenesis/Transfer Frontiers in pharmacology · 2022
    6. Incorporating Redox-Sensitive Nanogels Into Bioabsorbable Nanofibrous Membrane To Acquire ROS-Balance Capacity For Skin Regeneration Bioactive Materials · 2021
    7. Bioactive Molecules for Skin Repair and Regeneration: Progress and Perspectives Stem Cells International · 2019