Th22 Is the Effector Cell of Thymosin β15-Induced Hair Regeneration in Mice

    January 2024 in “ Inflammation and regeneration ”
    Nana Tao, Yuyuan Ying, X Xu … Jian‐Li Gao
    Studysummary This study identified Th22 cells as key effectors in hair regeneration driven by thymosin beta 15, suggesting they could be potential targets for hair regrowth therapies.
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    Research cited in this study 18

    1. Injury-Induced Interleukin-1 Alpha Promotes Lgr5 Hair Follicle Stem Cells Regeneration and Proliferation via Regulating Regenerative Microenvironment in Mice Inflammation and Regeneration · 2023
    2. Thymosin Beta 4 and Actin: Binding Modes, Biological Functions and Clinical Applications Current Protein and Peptide Science · 2022
    3. Alpinetin Promotes Hair Regeneration via Activating Hair Follicle Stem Cells Chinese medicine · 2022
    4. P63 Targeted Deletion Under the FOXN1 Promoter Disrupts Pre- and Post-Natal Thymus Development, Function, and Maintenance, and Induces Severe Hair Loss PloS one · 2022
    5. Multiple Potential Roles of Thymosin Beta 4 in the Growth and Development of Hair Follicles Journal of Cellular and Molecular Medicine · 2021
    6. Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation Frontiers in Cell and Developmental Biology · 2020
    7. The Overexpression of Tβ4 in the Hair Follicle Tissue of Alpas Cashmere Goats Increases Cashmere Yield and Promotes Hair Follicle Development Animals · 2019
    8. Alopecia Diffusa While Using Interleukin-17 Inhibitors Against Psoriasis Vulgaris Case Reports in Dermatology · 2019
    9. Use of Human Intra-Tissue Stem/Progenitor Cells and Induced Pluripotent Stem Cells for Hair Follicle Regeneration PubMed · 2019
    10. New Pattern Hair Loss in Young Turkish Women: What's Wrong in Their Daily Life? Skin Research and Technology · 2019
    11. Therapeutic Potential of Stem Cells in Follicle Regeneration Stem Cells International · 2018
    12. Tβ4-Overexpression Based on the PiggyBac Transposon System in Cashmere Goats Alters Hair Fiber Characteristics Transgenic research · 2016
    13. Decoction and Fermentation of Selected Medicinal Herbs Promote Hair Regrowth by Inducing Hair Follicle Growth in Conjunction with Wnt Signaling Evidence-based Complementary and Alternative Medicine · 2016
    14. Over-Expression of Thymosin Beta4 Promotes Abnormal Tooth Development and Stimulation of Hair Growth The International Journal of Developmental Biology · 2009
    15. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    16. Thymosin Beta 4 Induces Hair Growth Via Stem Cell Migration And Differentiation Annals of the New York Academy of Sciences · 2007
    17. Keratin 17 Modulates Hair Follicle Cycling in a TNFα-Dependent Fashion Genes & Development · 2006
    18. Thymosin Beta 4 Increases Hair Growth by Activation of Hair Follicle Stem Cells The FASEB Journal · 2003

    Related research 6

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle Experimental and Therapeutic Medicine · 2016
    3. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    4. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    5. Regeneration of Hair Follicles Is Modulated by Flightless I (Flii) in a Rodent Vibrissa Model Journal of Investigative Dermatology · 2010
    6. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006