Tβ4-Overexpression Based on the PiggyBac Transposon System in Cashmere Goats Alters Hair Fiber Characteristics

    November 2016 in “ Transgenic research ”
    Bingbo Shi, Qiang Ding, Xiaolin He, Haijing Zhu, Yaxiao Niu, Bei Cai, Jiao Cai, Anming Lei, Danju Kang, Hailong Yan, Baohua Ma, Xiaolong Wang, Qu Liu, Yulin Chen
    TLDR Overexpressing Tβ4 in cashmere goats improves hair fiber traits and increases cashmere yield.
    The study investigated the use of the piggyBac transposon system to overexpress thymosin beta-4 (Tβ4) in cashmere goats, aiming to enhance hair fiber characteristics. Researchers produced five transgenic goats using somatic cell nuclear transfer (SCNT) and found that these goats exhibited a higher secondary to primary hair follicle (S/P) ratio compared to wild type goats, indicating an increased number of secondary hair follicles (SHF). The findings suggested that Tβ4-overexpression could be a viable method to increase cashmere yield by improving hair fiber traits such as length and diameter.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    5 / 5 results

      community IGF-1 and Peptides? Miracle molecule waiting to be found

      in Research/Science  8 upvotes 4 days ago
      The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

      community Thoughts on a previous stack m

      in Product  3 upvotes 8 months ago
      The conversation discusses past and current hair loss treatments, with the user reflecting on expensive peptide treatments like topical Dutasteride, Latanoprost, and others, which were ultimately deemed less effective than oral Dutasteride and Minoxidil. The user now prefers the latter due to their cost-effectiveness and efficacy.

      community 8 years of hair loss, turning 30 next month

      in Progress Pictures  153 upvotes 1 month ago
      The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

      community How does low level laser therapy?

      in Chat  5 upvotes 5 months ago
      Low-level laser therapy (LLLT) is debated for hair regrowth, with some users suggesting it should be combined with treatments like minoxidil and finasteride for effectiveness. Many users express skepticism about LLLT's efficacy and cost, emphasizing the need for the correct wavelength and quality devices.

    Related Research

    5 / 5 results