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GlossarySomatic Cell Nuclear Transfer

involves transferring a somatic cell nucleus into an enucleated egg

Somatic Cell Nuclear Transfer (SCNT) is a laboratory technique where the nucleus of a somatic cell (a non-reproductive cell) is transferred into an egg cell that has had its own nucleus removed. This process can be used for cloning animals or for therapeutic purposes, such as generating stem cells that are genetically identical to the donor organism.

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research Production of Artificial Synthetic Spidroin Gene 4S-Transgenic Cloned Sheep Embryos Using Somatic Cell Nuclear Transfer

16 citations , March 2020 in “Animal Biotechnology”

Transgenic sheep embryos with a specific promoter were successfully created, but more research is needed for gene expression in hair follicles.

research Construction of Cashmere Goat Embryos Carrying K2.9 Gene by Transgenic Somatic Cell Nuclear Transfer Technology

January 2012 in “Zhongguo nongye Kexue”

The technology can create transgenic cashmere goats with improved wool quality.

research Tβ4-Overexpression Based on the PiggyBac Transposon System in Cashmere Goats Alters Hair Fiber Characteristics

18 citations , November 2016 in “Transgenic research”

Overexpressing Tβ4 in cashmere goats improves hair fiber traits and increases cashmere yield.

research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus

3 citations , January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu”

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

research Kantian Logic in Classical Social Theory: Society as a Source of Causality and the Ontology of Becoming

January 2008 in “Vestnik Tomskogo gosudarstvennogo universiteta Filologiya”

Overexpressing the Tβ4 gene in goats can increase cashmere production.

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community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community When you're balding is it an absolute traumatic period of your life or do some people not care as much?

in Chat 88 upvotes 1 year ago

Balding can be traumatic for many, affecting self-esteem and social interactions, while others accept it more easily. Treatments mentioned include finasteride, minoxidil, and RU58841.

community I can't take it anymore, thinking about the worst

in Finasteride/Dutasteride 13 upvotes 11 months ago

The individual is struggling with hair loss and depression, having tried treatments like Finasteride, Dutasteride, and Minoxidil, but faced side effects and limited success. They are considering a hair transplant and other options while dealing with personal challenges, including knee injuries and weight issues, and are encouraged by others to focus on self-improvement and acceptance.

community What should we lookout for in the near future for hairloss?

in Research/Science 17 upvotes 2 years ago

The user is using finasteride and minoxidil for hair loss but is looking for new treatments. Pyrilutamide and GT20029 are potential future treatments, with Pyrilutamide expected next year and GT20029 possibly by 2027.

community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

in Research/Science 11 upvotes 11 months ago

Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

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