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    Glossary Somatic Cell Nuclear Transfer

    involves transferring a somatic cell nucleus into an enucleated egg

    Somatic Cell Nuclear Transfer (SCNT) is a laboratory technique where the nucleus of a somatic cell (a non-reproductive cell) is transferred into an egg cell that has had its own nucleus removed. This process can be used for cloning animals or for therapeutic purposes, such as generating stem cells that are genetically identical to the donor organism.

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    1. Production of artificial synthetic spidroin gene 4S-transgenic cloned sheep embryos using somatic cell nuclear transfer Animal Biotechnology · 2020 · 16 citations
    2. Construction of Cashmere Goat Embryos Carrying K2.9 Gene by Transgenic Somatic Cell Nuclear Transfer Technology Zhongguo nongye Kexue · 2012
    3. Tβ4-overexpression based on the piggyBac transposon system in cashmere goats alters hair fiber characteristics Transgenic research · 2016 · 18 citations
    4. Hairless-knockout piglets generated using the clustered regularly interspaced short palindromic repeat/CRISPR-associated-9 exhibit abnormalities in the skin and thymus 2019 · 3 citations
    5. Кантианская логика в классической социальной теории: общество как источник причинности и онтология становления Vestnik Tomskogo gosudarstvennogo universiteta Filologiya · 2008
    6. Regulation of somatic cell reprogramming through inducible mir-302 expression Nucleic acids research · 2010 · 308 citations
    7. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    8. Role of β-Catenin Activation Levels and Fluctuations in Controlling Cell Fate Genes · 2019 · 28 citations
    9. Effect of Flightless I Expression on Epidermal Stem Cell Niche During Wound Repair Advances in Wound Care · 2019 · 10 citations
    10. Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease Stem cell biology and regenerative medicine · 2018
    11. Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity Cellular and Molecular Life Sciences · 2012 · 26 citations
    12. Function of KLF4 in Stem Cell Biology InTech eBooks · 2013 · 5 citations
    13. Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors International Journal of Molecular Medicine · 2013 · 56 citations
    14. Androgen Receptor Mutations and Polymorphisms in African American Prostate Cancer International Journal of Biological Sciences · 2014 · 23 citations
    15. Ichthyosis with confetti: clinics, molecular genetics and management Orphanet Journal of Rare Diseases · 2015 · 36 citations
    16. Systemic humoral activation facilitates tissue regeneration by D-chiral biomaterial scaffolds Cell Biomaterials · 2026
    17. Exosomes for repair, regeneration and rejuvenation Expert Opinion on Biological Therapy · 2015 · 135 citations
    18. Fatal autoimmunity results from the conditional deletion of Snai2 and Snai3 Cellular immunology · 2015 · 8 citations
    19. YAP1 promotes adipogenesis by regulating the negative feedback mechanism of the Hippo signaling pathway via LATS2 动物学研究 · 2025 · 2 citations
    20. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis Stem Cell Research & Therapy · 2019 · 26 citations
    21. Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression Cancer Research · 2006 · 176 citations
    22. Differentiation of Human Pluripotent Stem Cells Into Definitive Endoderm Cells in Various Flexible Three-Dimensional Cell Culture Systems: Possibilities and Limitations Frontiers in Cell and Developmental Biology · 2021 · 13 citations
    23. Generation of iPS Cells from Human Hair Follice Dermal Papilla Cells. PubMed · 2014 · 8 citations
    24. Generation of Cashmere Goats Carrying an <i>EDAR</i> Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing International Journal of Biological Sciences · 2018 · 33 citations
    25. Perspectives in dermatopathology: telomeres and telomerase in ageing and cancer; with emphasis on cutaneous disease Journal of Cutaneous Pathology · 2000 · 11 citations
    26. Transcriptome Profiling of Human Follicle Dermal Papilla Cells in response to Porphyra-334 Treatment by RNA-Seq Evidence-based complementary and alternative medicine · 2021 · 7 citations
    27. The Use of Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryos during Organogenesis and Their Role in Regulating the Gene Expression of Normal and Pathological (Stem) Cells International Journal of Molecular Sciences · 2020 · 3 citations
    28. Finasteride Enhances Stem Cell Signals of Human Dermal Papilla Cells in Vivo · 2019 · 10 citations
    29. Regulation of melanocyte stem cell behavior by the niche microenvironment Pigment Cell & Melanoma Research · 2018 · 24 citations
    30. A family business: stem cell progeny join the niche to regulate homeostasis Nature Reviews Molecular Cell Biology · 2012 · 254 citations