Disruption of Anthrax Toxin Receptor 1 in Pigs Leads to a Rare Disease Phenotype and Protection from Senecavirus A Infection

    March 2022 in “ Scientific reports ”
    Paula Chen, Raymond R. R. Rowland, Ana M. M. Stoian … Randall S. Prather
    Studysummary In this study, researchers found that pigs with genetically disrupted ANTXR1 were resistant to Senecavirus A infection, showing no clinical symptoms, and provided a model for human GAPO syndrome, while confirming ANTXR1 as a receptor for the virus.
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