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GlossarySomatic Cell Nuclear Transfer (SCNT)

involves transferring a somatic cell nucleus into an enucleated egg

Somatic Cell Nuclear Transfer (SCNT) is a laboratory technique where the nucleus of a somatic cell (a non-reproductive cell) is transferred into an egg cell that has had its own nucleus removed. This process can be used for cloning animals or for therapeutic purposes, such as generating stem cells that are genetically identical to the donor organism.

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research Tβ4-Overexpression Based on the PiggyBac Transposon System in Cashmere Goats Alters Hair Fiber Characteristics

18 citations, November 2016 in “Transgenic research”

Overexpressing Tβ4 in cashmere goats improves hair fiber traits and increases cashmere yield.

The Overexpression of Tβ4 in the Hair Follicle Tissue of Alpas Cashmere Goats Increases Cashmere Yield and Promotes Hair Follicle Development

research The Overexpression of Tβ4 in the Hair Follicle Tissue of Alpas Cashmere Goats Increases Cashmere Yield and Promotes Hair Follicle Development

16 citations, December 2019 in “Animals”

Overexpressing Tβ4 in goats' hair follicles increases cashmere production and hair follicle growth.

research Hairless-Knockout Piglets Generated Using CRISPR/Cas9 Exhibit Abnormalities in Skin and Thymus

3 citations, January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu”

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

research Next Generation Human Skin Constructs as Advanced Tools for Drug Development

69 citations, June 2017 in “Experimental Biology and Medicine”

Advanced human skin models improve drug development and could replace animal testing.

research The Pharmacology of Regenerative Medicine

47 citations, July 2013 in “Pharmacological Reviews”

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

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