November 2024 in “Open Repository of the University of Porto (University of Porto)” Tailored medication preparation and ongoing education are crucial for effective treatments.
1 citations
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November 2021 in “IntechOpen eBooks” This review covers red light Transcranial LED therapy for hippocampal memory impairment in aging and Alzheimer's but reports no clinical results, highlighting a need for further research into its mechanisms and effects.
In this study, young adult male albino rats treated with finasteride showed a 10% reduction in thickness of the CA1 layer of the hippocampus, suggesting that this atrophy may contribute to memory impairments linked to Post-Finasteride Syndrome.
81 citations
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June 2006 in “Experimental Neurology” Neurosteroids may help prevent seizures in epilepsy.
47 citations
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January 2016 in “Brain Behavior and Immunity” 5α-reduced progestogens may reduce mood issues and brain damage linked to HIV-1 Tat.
2 citations
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April 2024 in “Journal of Clinical Psychopharmacology” In this study, dutasteride 1 mg daily reduced heavy drinking days and drinks per week among treatment-seeking men, particularly benefiting those with high baseline drinking to cope motives.
November 2016 in “Hair transplant forum international” This article summarizes Dr. Alan Jacobs's presentation at the 2016 ISHRS World Congress but reports no new research findings.
135 citations
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March 2000 in “Journal of Biological Chemistry” This review discusses the roles of the Agouti and Agouti-related proteins in pigmentation and energy regulation and reports no new experimental findings.
14 citations
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October 2015 in “Neurochemistry International” This study found that letrozole, an aromatase inhibitor, reduced the incidence and severity of PTZ-induced kindling seizures in mice, potentially due to its effects on 17β-estradiol and neurosteroid synthesis.
2 citations
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March 2025 in “Quantitative Imaging in Medicine and Surgery” In this study, patients with alopecia areata showed altered hypothalamic activity and connectivity, which may be linked to the neurophysiological basis of psychological stress experienced by these patients, as assessed by functional MRI and correlated with neuropsychological evaluations.
December 2024 in “Journal of Clinical Medicine” This review explores the hormonal factors linking polycystic ovary syndrome and psychiatric disorders, such as eating disorders, emphasizing a bidirectional relationship that necessitates a multidisciplinary treatment approach; it reports no new clinical results.
35 citations
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January 2005 in “Brain Research” This study indicates that progesterone’s anesthetic activity in PR knockout mice is not due to progesterone receptors but is partially mediated by the neurosteroid allopregnanolone through GABAA receptor potentiation.
10 citations
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September 2022 in “Psychiatry and Clinical Neurosciences” This review discusses post-acute sequelae of SARS-CoV-2 infection, highlighting the challenges in diagnosing and managing the variety of persistent symptoms, and reports no new clinical results.
2 citations
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April 2013 in “PubMed” This review discusses non-motor symptoms in autoimmune myasthenia gravis and associated thymomas, highlighting abnormal T-cell clones as a contributing factor, but reports no new clinical results.
1 citations
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July 2025 in “Frontiers in Veterinary Science” This study examined genetic adaptations in Tibetan sheep through whole-genome resequencing, identifying key genes related to hypoxia tolerance, wool color, and body size. These findings provide a foundation for future molecular breeding strategies to enhance wool quality and adaptive traits in these high-altitude environments.
292 citations
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April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
90 citations
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December 2007 in “Current Oncology” This review discusses management strategies for sexual side effects of aromatase inhibitors in postmenopausal breast cancer patients and reports no original clinical findings.
20 citations
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April 2022 in “Journal of Personalized Medicine” This study found that robotic training with the Ekso-GT significantly improved body representation and quality of life in spinal cord injury patients compared to conventional physical therapy.
9 citations
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January 2022 in “Biology” This study concluded that male mice are more susceptible to valproic acid-induced autism spectrum disorder than female mice, with noticeable differences in brain histoarchitecture and receptor protein levels.
83 citations
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January 2004 in “Pharmacology & Therapeutics” This review explores the potential role of pregnane neurosteroids in modulating alcohol withdrawal symptoms, suggesting a therapeutic target for treating alcohol dependence, but reports no new clinical results.
34 citations
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August 2015 in “Frontiers in Behavioral Neuroscience” This study found that augmenting or reducing allopregnanolone activity in the BNST affected contextual fear expression in rats, suggesting sex differences in anxiety may be linked to neuroactive steroid regulation.
27 citations
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October 2018 in “Saudi Journal of Biological Sciences” This study found that curcumin administration improved cognitive and anxiety-related behaviors and neurochemical levels in HgCl2 exposed mice pups, suggesting protective effects against heavy metal-induced neurotoxicity.
14 citations
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September 2017 in “Hormones and behavior” This study found that the estrous cycle influences the effect of the δ-GABAAR agonist THIP in reducing binge drinking behavior in female mice, with receptor expression elevated during diestrus.
7 citations
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April 2021 in “Journal of Bodywork and Movement Therapies” This editorial reviews the concept of central sensitization and central sensitivity syndromes, discussing their potential role linking various chronic conditions, but it reports no new clinical findings.
3 citations
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July 2023 in “International journal of molecular sciences” This review discusses the association between emotional stress-related neuropeptides and the pathogenesis of alopecia areata, reporting no new experimental findings.
January 2026 in “International Journal of Molecular Sciences” This narrative review highlights that declining testosterone levels are a complex public health issue potentially influenced by modifiable lifestyle factors and environmental stressors, suggesting integrated strategies may be needed to address the trend's impacts on health.
January 2024 in “Metabolites” This review highlights the importance of standardizing pre-analytical procedures for collecting and extracting samples from uncommon biological specimens like breast milk and sweat in clinical metabolomics, to enhance diagnostic and biomarker discovery efforts while minimizing contamination and bias.
February 2024 in “Biomedicines” This study found that NKB placental mRNA expression was higher in women with PCOS, particularly in pregnancies with female offspring, suggesting its involvement in PCOS-related placental dysfunction.
September 2021 in “Physiology News” This abstract provides template specifications for design materials but reports no new research findings.
180 citations
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June 2004 in “Journal of Pharmacology and Experimental Therapeutics” This study found that progesterone's antiseizure effects in mice occurred primarily through conversion to allopregnanolone, rather than through the progesterone receptor, as evidenced by results in PR knockout mice.