TLDR Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
The 2007 document discussed the management of sexual dysfunction in postmenopausal breast cancer patients undergoing adjuvant aromatase inhibitor therapy. The therapy often led to sexual dysfunction due to diminished estrogen synthesis, causing symptoms like hot flushes, vaginal dryness, painful intercourse, and loss of sexual interest. Non-hormonal alternatives were recommended as first-line therapy for urogenital symptoms, with hormonal interventions considered if these failed. The document also discussed the potential benefits and risks of hormone therapy, including testosterone therapy, which required close monitoring for skin and hair problems, including androgenic alopecia. The document emphasized the importance of a biopsychosocial approach to assessment and management, including education, lifestyle changes, sexual counselling, pelvic floor therapies, sexual aids, medications, and dietary supplements.
282 citations,
October 2006 in “The Journal of Clinical Endocrinology and Metabolism” The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
100 citations,
July 2004 in “The Journal of Sexual Medicine” Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
20 citations,
April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
883 citations,
August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
1514 citations,
December 2011 in “Fertility and sterility” Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.
There are many ways to treat Polycystic Ovary Syndrome, including lifestyle changes, surgery, and various medications, but more research is needed for better treatments.
17 citations,
December 2020 in “Journal of Genetic Counseling” Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.
