Endocrine Aspects of Female Sexual Dysfunction

    July 2004 in “ The Journal of Sexual Medicine ”
    Susan Ruth Davis, André T. Guay, Jan L. Shifren, Norman A. Mazer
    Image of study
    TLDR Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.
    The 2004 study "Endocrine Aspects of Female Sexual Dysfunction" investigated the role of hormones in female sexual function. It found that hormones such as estrogen, testosterone, progesterone, and prolactin have complex roles in this area. Sex steroid insufficiency was linked to urogenital atrophy and could negatively impact central sexual thought processes. While systemic estrogen/estrogen progestin therapy was found to alleviate climacteric symptoms, it did not specifically improve hypoactive sexual desire disorder (HSDD) in premenopausal or postmenopausal women. Exogenous testosterone was shown to improve sexual desire, arousal, and satisfaction in small randomized controlled trials. However, the study concluded that more research was needed to define safe and effective endocrine treatments for female sexual dysfunction. The paper also called for improved methods for measuring total and free testosterone in women, establishing normal ranges for various androgens in women, and studying the long-term safety of exogenous testosterone, particularly its effects on hair and skin.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 690 results

      community Nandrolone Replacement Therapy

      in Treatment  41 upvotes 1 year ago
      A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  111 upvotes 8 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community I think we all hop on estrogen. It's the only angle

      in Satire  83 upvotes 3 months ago
      The conversation humorously discusses hair loss treatments, including Minoxidil, finasteride, RU58841, and topical 17 alpha estradiol, with some users joking about transitioning to female to avoid baldness. The overall tone is satirical, emphasizing self-acceptance and the lengths people might consider for hair restoration.

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  36 upvotes 5 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

    Similar Research

    5 / 1000+ results