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GlossaryDecreased Libido (HSDD)

reduced interest in sexual activity

Decreased libido, also known as low libido or reduced sex drive, refers to a diminished interest in sexual activity. This condition can be influenced by various factors, including hormonal imbalances, psychological issues such as stress or depression, certain medications, and underlying medical conditions. Understanding the root cause is essential for effective treatment, which may involve lifestyle changes, therapy, or medical interventions.

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FDA-Approved (Bremelanotide, Flibanserin) and Off-Label Medications (Testosterone, Sildenafil) to Enhance Sexual Desire and Function in Women

research FDA-Approved (Bremelanotide, Flibanserin) and Off-Label Medications (Testosterone, Sildenafil) to Enhance Sexual Desire and Function in Women

April 2020 in “Online journal of complementary & alternative medicine”

Some medications can help increase sexual desire and function in women.

International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women

research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women

30 citations, April 2021 in “The Journal of Sexual Medicine”

Testosterone therapy can help postmenopausal women with low sexual desire if monitored carefully.

research International Society for the Study of Women's Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder in Women

20 citations, April 2021 in “Journal of Womens Health”

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

Testosterone Therapy for Women with Low Sexual Desire: A Position Statement from the Brazilian Society of Endocrinology and Metabolism

research Testosterone Therapy for Women with Low Sexual Desire: A Position Statement from the Brazilian Society of Endocrinology and Metabolism

10 citations, January 2019 in “Archives of Endocrinology and Metabolism”

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline

251 citations, October 2014 in “The Journal of Clinical Endocrinology & Metabolism”

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

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