Neurobehavioral Protective Properties of Curcumin Against Mercury Chloride Treated Mice Offspring

    October 2018 in “ Saudi Journal of Biological Sciences ”
    Gasem Mohammad Abu-Taweel
    TLDR Curcumin can protect against mercury's harmful effects on brain and behavior.
    The study examined the neurobehavioral impact of mercury chloride (HgCl2) on mice offspring and the protective effects of curcumin. HgCl2 exposure resulted in significant developmental and neurobehavioral deficits, including reduced body weight, delayed physical development, impaired neuromotor maturation, and increased anxiety. Biochemical analyses showed depleted neurotransmitter levels and increased oxidative stress. Curcumin administration significantly mitigated these effects, indicating its protective role against mercury-induced neurotoxicity. The study suggested curcumin could help counteract the toxic effects of mercury and other heavy metals, though further research was needed to fully understand its benefits.
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