Celery Ameliorating Against Neurobehavioral and Neurochemical Disorders of Perinatal Lipopolysaccharides Exposure in Mice Offspring

The study explored the protective effects of celery on neurobehavioral and neurochemical disorders in mice offspring exposed to lipopolysaccharides (LPS) perinatally. LPS exposure led to reduced body weight, delayed eye opening and hair development, impaired neuromotor maturation, and memory and learning disorders, along with decreased neurotransmitter levels and increased oxidative stress. Celery administration significantly alleviated these adverse effects, enhancing physical development, neuromotor reflexes, cognitive functions, and biochemical parameters. The findings indicated that celery had a protective role against LPS-induced developmental and neurobehavioral toxicity in mice, suggesting its potential as a protective agent against such toxins.