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    Glossary Acetylcholinesterase

    breaks down acetylcholine in the synaptic cleft

    Acetylcholinesterase (AChE) is an enzyme that breaks down the neurotransmitter acetylcholine in the synaptic cleft, which is the space between nerve cells. This process is crucial for terminating nerve impulses and allowing muscles to relax after contraction. Inhibiting AChE can lead to prolonged muscle contraction and is a mechanism used by certain nerve agents and pesticides.

    Research 10 of 194

    1. Finasteride Has Regionally Different Effects on Brain Oxidative Stress and Acetylcholinesterase Activity in Acute Thioacetamide-Induced Hepatic Encephalopathy in Rats PLOS ONE · 2015 · 11 citations
    2. Development and Validation of an HPLC-PDA Method for Quantitation of Ten Marker Compounds from Eclipta prostrata (L.) and Evaluation of Their Protein Tyrosine Phosphatase 1B, α-Glucosidase, and Acetylcholinesterase Inhibitory Activities Natural Product Sciences · 2020 · 4 citations
    3. Anti-acetylcholinesterase and Antioxidant Effects of Identified Compounds from Houttuynia cordata The Korean Tea Society · 2022
    4. The effects of finasteride (FIN) and thioacetamide (TAA) on acetylcholinesterase (AchE) activity in various brain regions. PLOS ONE · 2015
    5. Baiting Proteins with C<sub>60</sub> ACS Nano · 2010 · 106 citations
    6. Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring Saudi Journal of Biological Sciences · 2018 · 27 citations
    7. A network pharmacology-based approach to explore mechanism of action of medicinal herbs for alopecia treatment Scientific Reports · 2022 · 8 citations
    8. Acquired Localized Hypertrichosis Induced by Rivastigmine Case reports in dermatological medicine · 2016 · 3 citations
    9. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    10. The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth International Journal of Molecular Sciences · 2026
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