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    Glossary Acetylcholinesterase

    breaks down acetylcholine in the synaptic cleft

    Acetylcholinesterase (AChE) is an enzyme that breaks down the neurotransmitter acetylcholine in the synaptic cleft, which is the space between nerve cells. This process is crucial for terminating nerve impulses and allowing muscles to relax after contraction. Inhibiting AChE can lead to prolonged muscle contraction and is a mechanism used by certain nerve agents and pesticides.

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    Research 30 of 173

    1. Finasteride Has Regionally Different Effects on Brain Oxidative Stress and Acetylcholinesterase Activity in Acute Thioacetamide-Induced Hepatic Encephalopathy in Rats PLOS ONE · 2015 · 11 citations
    2. Development and Validation of an HPLC-PDA Method for Quantitation of Ten Marker Compounds from Eclipta prostrata (L.) and Evaluation of Their Protein Tyrosine Phosphatase 1B, α-Glucosidase, and Acetylcholinesterase Inhibitory Activities Natural Product Sciences · 2020 · 4 citations
    3. Anti-acetylcholinesterase and Antioxidant Effects of Identified Compounds from Houttuynia cordata The Korean Tea Society · 2022
    4. The effects of finasteride (FIN) and thioacetamide (TAA) on acetylcholinesterase (AchE) activity in various brain regions. PLOS ONE · 2015
    5. Baiting Proteins with C<sub>60</sub> ACS Nano · 2010 · 106 citations
    6. Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring Saudi Journal of Biological Sciences · 2018 · 27 citations
    7. A network pharmacology-based approach to explore mechanism of action of medicinal herbs for alopecia treatment Scientific Reports · 2022 · 8 citations
    8. Acquired Localized Hypertrichosis Induced by Rivastigmine Case reports in dermatological medicine · 2016 · 3 citations
    9. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    10. The Muscarinic Acetylcholine Receptor in Dermal Papilla Cells Regulates Hair Growth International Journal of Molecular Sciences · 2026
    11. The muscarinic acetylcholine receptor in dermal papilla cells regulates hair growth 2024
    12. Caffeic Acid attenuates acrylamide induced biochemical, hematological and histological alterations in rats Research Square (Research Square) · 2022
    13. Enzyme Inhibitory Activities of Marine Sponges Against Cholinesterase and 5α-Reductase 2019
    14. Phytochemical profiling, green synthesis of Ag, Cu, Fe, and Zn nanoparticles, and in vitro biological activities of Delphinium brunonianum Royle Scientific Reports · 2026
    15. GC–MS Profiling, Antioxidant, Enzyme Inhibition, Molecular Docking, and ADME Investigation of the <i>n</i> ‐Hexane Extract and the Essential Oil of <i>Platycladus orientalis</i> (L.) Franco Fruits Chemistry & Biodiversity · 2026
    16. Larvicidal potential, antimicrobial properties and molecular docking analysis of Egyptian Mint (Mentha rotundifolia) against Culex pipiens L. (Diptera: Culicidae) and Midgut-borne Staphylococcus aureus Scientific reports · 2024
    17. Assessment of the Chemical Profile and Potential Medical Effects of a Flavonoid-Rich Extract of Eclipta prostrata L. Collected in the Central Highlands of Vietnam Pharmaceuticals · 2023 · 6 citations
    18. EFFECT OF ECLIPTA ALBA ON SCOPOLAMINE INDUCED AMNESIA IN MICE Journal of Drug Delivery and Therapeutics · 2018 · 5 citations
    19. Celery ameliorating against neurobehavioral and neurochemical disorders of perinatal lipopolysaccharides exposure in mice offspring Journal of King Saud University - Science · 2020 · 7 citations
    20. Antioxidant and Cholinesterase Inhibitory Activity of a New Peptide From <i>Ziziphus jujuba</i> Fruits American Journal of Alzheimer s Disease & Other Dementias® · 2013 · 69 citations
    21. Pharmacological Efficacy of Tamarix aphylla: A Comprehensive Review Plants · 2021 · 20 citations
    22. PEGylated Flavonoid Aspasomes as a Brain-Targeted Nano-Vesicular Platform for Enhanced Neuroprotection in Stress-Induced Cognitive Dysfunction AAPS PharmSciTech · 2026
    23. Experimental and Clinical Pharmacology of<i>Ziziphus jujuba</i>Mills Phytotherapy Research · 2017 · 31 citations
    24. The potential involvement of cholinergic system in finasteride induced cognitive dysfunction Psychoneuroendocrinology · 2020
    25. Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances Pharmacological Research · 2019 · 112 citations
    26. HPLC-ESI-MSn characterization of phenolic compounds, terpenoid saponins, and other minor compounds in Bituminaria bituminosa Industrial Crops and Products · 2015 · 76 citations
    27. Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang International Journal of Molecular Sciences · 2021 · 26 citations
    28. Protective Role of Nutritional Plants Containing Flavonoids in Hair Follicle Disruption: A Review International Journal of Molecular Sciences · 2020 · 24 citations
    29. An update review on Hibiscus rosa sinensis phytochemistry and medicinal uses Journal of Ayurvedic and herbal medicine · 2018 · 24 citations
    30. Phytochemical, Toxicological and Pharmacological Studies of <i>Asiasari Radix</i> et Rhizoma: A Review Tropical Journal of Pharmaceutical Research · 2015 · 17 citations