Endogenous Neurosteroids Modulate Epileptogenesis in a Model of Temporal Lobe Epilepsy

    June 2006 in “ Experimental Neurology ”
    Giuseppe Biagini, Enrica Baldelli, Daniela Longo … Massimo Avoli
    Studysummary Neurosteroids may help prevent seizures in epilepsy.
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    Research cited in this study 2

    1. Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice Journal of Pharmacology and Experimental Therapeutics · 2004
    2. Finasteride, a 5alpha-Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice PubMed · 1999

    Related research 2

    1. Finasteride Inhibits the Disease-Modifying Activity of Progesterone in the Hippocampus Kindling Model of Epileptogenesis Epilepsy & Behavior · 2012
    2. Finasteride Inhibits the Progesterone-Induced Spike-Wave Discharges in a Genetic Model of Absence Epilepsy Pharmacology, Biochemistry and Behavior · 2003