Polycystic Ovary Syndrome and Eating Disorders: A Literature Review

    December 2024 in “ Journal of Clinical Medicine
    Agata Góral, Klaudia Żywot, Wojciech Zalewski, Adam Jagodziński, Marek Murawski
    TLDR PCOS and eating disorders are linked by hormonal imbalances, needing personalized treatment.
    This literature review examines the intricate relationship between polycystic ovary syndrome (PCOS) and eating disorders (EDs), focusing on hormonal imbalances involving serotonin, leptin, insulin, ghrelin, kisspeptin, and cortisol. These imbalances contribute to the development of EDs, such as bulimia and binge eating, in women with PCOS. The review highlights that serotonin deficiency and leptin fluctuations are linked to mood and eating disorders, while elevated kisspeptin and hyperinsulinemia worsen hormonal dysregulation. The bidirectional relationship between PCOS and EDs suggests the need for a multidisciplinary treatment approach, early identification, and personalized interventions. Future research should aim to clarify the hormonal mechanisms to improve treatment strategies and quality of life for women with PCOS.
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