Dehydrogenase, Cortisol, Dopamine, Zinc, and Vitamin D3 in Iraqi Patients with Polycystic Ovary Syndrome

    February 2025 in “ Iraqi Journal of Science ”
    Nuruddin Mohammed, Ghassan M. Sulaiman, Hazima Mossa Alabassi
    Image of study
    TLDR PCOS patients have higher LDH and lower cortisol, dopamine, zinc, and vitamin D3, which may contribute to their symptoms and obesity.
    The study examined 138 women, including 90 with PCOS and 48 healthy controls, and found that PCOS patients had higher levels of lactate dehydrogenase (LDH) and lower levels of cortisol, dopamine, zinc, and vitamin D3 compared to controls. These biochemical differences may contribute to the pathogenesis of PCOS, which is associated with symptoms like irregular menstruation and excessive hair growth. The study also noted a higher prevalence of obesity in PCOS patients, suggesting that these biochemical and anthropometric differences could play a role in the condition's pathophysiology and related reproductive challenges.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 44 results
      PP405 Identity Research

      community PP405 Identity Research

      by UmbrellaLabsResearch in Research  292 upvotes 7 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community My summation of PP405 - looks promising

      in Research/Science  210 upvotes 1 year ago
      PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 6 months ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community The Cure isn't 5 years away; it's already here.

      in Research/Science  1005 upvotes 1 year ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

    Similar Research

    5 / 866 results