Dehydrogenase, Cortisol, Dopamine, Zinc, and Vitamin D3 in Iraqi Patients with Polycystic Ovary Syndrome

    February 2025 in “ Iraqi Journal of Science
    Nuruddin Mohammed, Ghassan M. Sulaiman, Hazima Mossa Alabassi
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    Hydrocortisone →

    a synthetic cortisol used for anti-inflammatory effects

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    Studysummary This study found that women with polycystic ovary syndrome had significantly higher serum lactate dehydrogenase levels and lower levels of cortisol, dopamine, zinc, and vitamin D3 compared to healthy controls.
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    The study examined 138 women, including 90 with PCOS and 48 healthy controls, and found that PCOS patients had higher levels of lactate dehydrogenase (LDH) and lower levels of cortisol, dopamine, zinc, and vitamin D3 compared to controls. These biochemical differences may contribute to the pathogenesis of PCOS, which is associated with symptoms like irregular menstruation and excessive hair growth. The study also noted a higher prevalence of obesity in PCOS patients, suggesting that these biochemical and anthropometric differences could play a role in the condition's pathophysiology and related reproductive challenges.
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