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GlossaryLactate Dehydrogenase (LDH)

enzyme that converts lactate to pyruvate in cells

Lactate Dehydrogenase (LDH) is an enzyme that plays a crucial role in converting sugar into energy for cells, particularly during anaerobic respiration when oxygen levels are low. Elevated levels of LDH in the blood can indicate tissue damage or disease, as it is released from cells into the bloodstream when they are damaged.

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research Hepatoprotective Activity of Yellow Chinese Chive Against Acetaminophen-Induced Acute Liver Injury via Nrf2 Signaling Pathway

2 citations , August 2020 in “Journal of Nutritional Science and Vitaminology”

Yellow Chinese chive extract helps protect mouse livers from damage caused by acetaminophen by activating an antioxidant pathway.

research A Simple Assay for the Study of Human Hair Follicle Damage Induced by Ionizing Irradiation

16 citations , November 2009 in “Experimental dermatology”

Ionizing radiation damages human hair follicles by stopping cell growth, causing cell death, disrupting color, and increasing stress and damage markers.

research Dehydrogenase, Cortisol, Dopamine, Zinc, and Vitamin D3 in Iraqi Patients with Polycystic Ovary Syndrome

February 2025 in “Iraqi Journal of Science”

PCOS patients have higher LDH and lower cortisol, dopamine, zinc, and vitamin D3, which may contribute to their symptoms and obesity.

research A Drug-Free, Hair Follicle Cycling Regulatable, Separable, Antibacterial Microneedle Patch for Hair Regeneration Therapy

31 citations , July 2022 in “Advanced healthcare materials/Advanced Healthcare Materials”

A drug-free microneedle patch significantly promotes hair growth and prevents infections.

research N1-Methylspermidine, A Stable Spermidine Analog, Prolongs Anagen And Regulates Epithelial Stem Cell Functions In Human Hair Follicles

13 citations , July 2015 in “Archives of dermatological research”

N1-methylspermidine helps hair growth and reduces inflammation in hair follicles.

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community Debunk the debunk ? - Not sure but this study still exists ...

in Research/Science 25 upvotes 4 years ago

The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841. It highlights a study suggesting that sulforaphane may reduce DHT levels and promote hair growth in mice.

community Possible natural pp405 solution

in Research/Science 45 upvotes 6 months ago

Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 486 upvotes 1 year ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community PP405 - hair stem cell stimulation

in Research/Science 53 upvotes 2 years ago

PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

in Research/Science 1 month ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

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