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    GlossaryLactate Dehydrogenase (LDH)

    enzyme that converts lactate to pyruvate in cells

    Lactate Dehydrogenase (LDH) is an enzyme that plays a crucial role in converting sugar into energy for cells, particularly during anaerobic respiration when oxygen levels are low. Elevated levels of LDH in the blood can indicate tissue damage or disease, as it is released from cells into the bloodstream when they are damaged.

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      community Possible natural pp405 solution

      in Research/Science  45 upvotes 1 month ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community PP405 - hair stem cell stimulation

      in Research/Science  49 upvotes 1 year ago
      PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.

      community The mechanism of androgenic alopecia

      in Research/Science  32 upvotes 1 week ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.