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The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Polymeric nanoparticles show promise for treating skin diseases.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

The Rotterdam Study aims to understand various diseases in older adults.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.