Prediction of Cell States and Key Transcription Factors of the Human Cornea Through Integrated Single-Cell Omics Analyses

    July 2025 in “ PNAS Nexus
    J.A. Arts, Sofia Fallo, Melanie S. Florencio, Jos G.A. Smits, Dulce Lima Cunha, Janou A. Y. Roubroeks, Mor M. Dickman, Vanessa L.S. LaPointe, Rosemary Yu, Huiqing Zhou
    Studysummary This study integrated single-cell RNA-seq data from four previous studies to create a comprehensive human corneal cell state meta-atlas, revealing novel marker genes, rare cell states, and distinct transcription factors, and offering a tool to enhance future cornea research.
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