87 citations
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July 2007 in “British Journal Of Nutrition” In this study, oral administration of Lactococcus lactis strain H61 to senescence-accelerated mice was linked to reduced bone density loss, less skin ulcer incidence, and reduced hair loss, along with altered immune responses.
October 2025 in “Burns & Trauma” This review highlights recent advancements in engineered probiotics for wound healing, reporting that genetically engineered strains of Lactobacillus reuteri and Lactococcus cremoris have shown promise in promoting faster wound healing in pre-clinical and clinical settings, particularly for diabetic foot ulcers.
30 citations
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January 1994 This study found that oral administration of Lactococcus lactis subsp. cremoris H61 to aged mice was associated with reduced bone loss, fewer skin ulcers, and less hair loss compared with controls.
6 citations
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July 2021 in “Microbial biotechnology” This study found that combining LED yellow light with an engineered strain expressing CXCL12 improved wound healing and reduced inflammation in a mouse model of scald wounds.
63 citations
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September 2020 in “Frontiers in Microbiology” This review discusses the potential health benefits of probiotics as a "Bio-Therapy" in food and medicine, noting that more research is needed to fully understand their mechanisms and effectiveness.
12 citations
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March 2022 in “Antioxidants” This study found that encapsulating tamarillo polyphenols in cubosome nanoparticles protected them during digestion and enhanced the nutritional and antioxidant properties of yoghurt when used as a delivery system.
3 citations
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June 2025 in “Biomedicines” This review discusses the potential link between gut microbiota alterations and the onset and progression of alopecia areata, identifying it as a possible pathogenetic factor and therapeutic target, but reports no new clinical results.
20 citations
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March 2023 in “Drug Delivery and Translational Research” This study found that a lacticin 3147 solid lipid nanoparticle gel demonstrated potent and sustained antimicrobial activity against S. aureus, including MRSA, in ex vivo S. aureus-infected pig skin.
September 2025 in “Institutional Repositories DataBase (IRDB)” Lactic acid bacteria fermentation can turn waste into valuable skincare ingredients.
April 2026 in “International Journal of Drug Delivery Technology” This study found that Lactobacillus acidophilus cell-free supernatant caused significant cytotoxicity, reduced migratory ability, and induced apoptosis in cervical cancer cell lines, suggesting its potential as a non-toxic adjunct therapy for cervical cancer.
2 citations
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October 2023 in “Animals” Lacto-fermentation changes amino acid profiles in bovine colostrum, but results are inconsistent.
January 2013 in “Hunan Agricultural Sciences” In this study, Lactobacillus reuteri and Bacillus natto were found to potentially replace Aureomycin in alleviating weaning stress in piglets, based on growth, diarrhea rate, immunity, and other health indicators.
November 2023 in “Food science of animal resources” This study found that in mice, oral administration of Lactilactobacillus curvatus LB-P9 accelerated hair regrowth and increased hair thickness, hair follicle numbers, and dermal thickness, likely by boosting hair growth factor production and dermal papilla proliferation.
16 citations
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March 2023 in “Clinical Cosmetic and Investigational Dermatology” This study demonstrated that regular use of LactoSporin cream for 10 weeks significantly reduced wrinkles and fine lines in healthy female participants, although improvements in skin elasticity and hydration were not significantly better than placebo when measured by certain instruments.
March 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that probiotics, specifically the L. plantarum MTCC 1325 strain, may have protective effects against Alzheimer's-like symptoms induced by D-Galactose in animal models, suggesting potential therapeutic use for neurodegenerative disorders.
November 2025 in “Probiotics and Antimicrobial Proteins”
September 2021 in “Journal of skin and stem cell” Lactium, a milk protein, can help reduce symptoms of skin disorders linked to stress and anxiety without side effects.
5 citations
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April 2023 in “BMC Microbiology” This study found that using a shampoo containing heat-killed probiotics, GMNL-653, led to decreased dandruff and sebum production and increased hair growth in human participants, with observed microbiota shifts including changes in M. globosa and M. restricta abundance.
March 2025 in “Research Square (Research Square)” This study explored the potential of the lysate and lipoteichoic acid from Lactiplantibacillus plantarum APsulloc 331261 to improve scalp seborrheic dermatitis by modulating inflammatory and lipogenesis pathways in vitro, suggesting potential as a natural treatment option.
5 citations
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January 2024 in “Fermentation” This study found that fermenting porcine and equine placentas with a specific lactic acid bacterial strain enhanced the moisturizing abilities and cell proliferation properties compared to traditional placental extracts, suggesting their potential for cosmetic applications.
9 citations
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July 2021 in “Journal of Medicinal Food” This study found that consuming Lactobacillus paracasei HY7015 promoted hair growth and follicle maturation in mice, likely through stimulating dermal papilla cell proliferation and growth factor secretion.
January 2026 in “Physical Education Health and Social Sciences” This study found that integrating Lactobacillus-rich probiotic nutrition and fractional CO₂ laser therapy with clotrimazole in mucoadhesive hydrogels significantly improved clinical and structural outcomes for women with recurrent vulvovaginal candidiasis, suggesting a promising advanced therapy, though further validation in larger trials is needed.
34 citations
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April 2012 in “Molecular Biology Reports” This study isolated a thermophilic bacterial strain, Bacillus cereus, from soil that produces an extracellular protease; the enzyme effectively removed non-leather structures from animal pelts and was compatible with commercial detergents.
119 citations
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October 2011 in “Journal of Veterinary Internal Medicine” This review discusses the clinical manifestations and immune response to Rhodococcus equi infection in foals but reports no new clinical results.
1 citations
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February 2014 in “Revista de investigaciones veterinarias del Perú” This case study describes a Lop male rabbit with Malassezia-associated dermatitis, initially treated with griseofulvin but requiring ketoconazole for complete recovery after recurrence.
September 2023 in “Clinical, cosmetic and investigational dermatology” In this study, the researchers found that a 28-day topical treatment with a postbiotic ferment complex notably altered the scalp microbiome in women with sensitive scalps, increasing certain bacterial species and decreasing others, while also reportedly alleviating symptoms of sensitive skin syndrome in all participants.
8 citations
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February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
December 2023 in “Scientific reports” This study assessed three lactic acid bacteria-fermented proteins and found that F-WPI and F-SPI could normalize osteoclastogenesis markers in vitro, while F-SPI enhanced osteoblastogenesis markers, suggesting potential as dietary supplements for osteoporosis prevention, though further research into mechanisms is needed.
January 2026 in “Frontiers in Microbiology” This study suggests that Enterococcus faecium fermentation broth may have anti-aging effects in mice, mainly through modulating gut microbiota and enhancing immunity, with the key component NlpC/P60 potentially boosting host immune responses and increasing beneficial bacterial populations.
This study found that in individuals with alopecia, scalp microbial diversity decreased while Cutibacterium acnes abundance increased, and that treating Cutibacterium acnes-infected mice with Lactobacillus plantarum L30 improved hair follicle health and hair growth, suggesting a potential new treatment pathway for alopecia.