Lactobacillus Paracasei HY7015 Promotes Hair Growth in a Telogenic Mouse Model

    July 2021 in “ Journal of Medicinal Food
    Woo Dong Nam, Hyeonji Kim, Chuhyun Bae, Ji‐Soo Kim, Bora Nam, Joo-Yun Kim, Soo-Dong Park, Jung-Lyoul Lee, Jae-Hun Sim
    TLDR Lactobacillus paracasei HY7015 helps hair grow in mice.
    This study demonstrated that oral administration of Lactobacillus paracasei HY7015 promoted hair growth in a telogenic mouse model. HY7015 stimulated the proliferation of hair follicle dermal papilla cells (HFDPC) and increased the secretion of growth factors such as vascular endothelial growth factor and insulin-like growth factor-1. In mice, HY7015 enhanced hair growth and follicle maturation in the dorsal skin and elevated growth factor levels in serum. The findings suggested that L. paracasei HY7015 could promote hair growth by stimulating HFDPC proliferation and growth factor secretion, with further research needed to explore the underlying mechanisms.
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