1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
4 citations
,
January 2019 in “Annals of Dermatology” RE-ORGA, a Korean herb extract, may help prevent hair loss.
53 citations
,
July 2018 in “Drug design, development and therapy” Janus kinase inhibitors show promise in treating alopecia areata but need better topical formulations.
2 citations
,
June 2017 in “Journal of biomedicine and translational research” Lychee fruit polyphenol (Oligonol®) may regulate genes linked to cell growth and inflammation in human scalp cells.
1 citations
,
January 2022 in “Stem cell biology and regenerative medicine” New methods to test hair growth treatments have been developed.
47 citations
,
December 2019 in “Frontiers in immunology” A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
28 citations
,
April 2020 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
25 citations
,
November 2018 in “Journal of The American Academy of Dermatology” Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.
49 citations
,
October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
8 citations
,
July 2022 in “International Journal of Molecular Sciences” Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
April 2012 in “Journal of The American Academy of Dermatology” Higher levels of certain nerve-related proteins are linked to hair loss in women with scalp pain.
65 citations
,
June 2020 in “Stem Cell Research & Therapy” Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
10 citations
,
May 2021 in “Stem Cell Research & Therapy” Bone marrow-derived stem cells improved healing and reduced scarring in second-degree burns in rats.
3 citations
,
January 2011 in “Annals of Dermatology” Blocking EGFR in skin cells doesn't majorly increase inflammation markers.
May 2017 in “Journal of Investigative Dermatology” Cow milk sugars increase fat production and inflammation in skin oil cells.
June 2022 in “Frontiers in Immunology” Tofacitinib regrew hair in a man with total hair loss but raised cytokine levels, needing more research on possible side effects.
February 2024 in “ACS Omega” The Shen Bai Hair Growing Decoction may help treat hair loss by promoting hair growth and reducing inflammation.
64 citations
,
July 2016 in “Cold Spring Harbor Perspectives in Medicine” The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
1 citations
,
November 2015 in “Indian Journal of Clinical Biochemistry” The conference presented findings on how vitamin D levels, genetic factors, and lifestyle choices like smoking and yoga affect various health conditions and diseases.
26 citations
,
November 2016 in “Biomolecules & Therapeutics” 3-Deoxysappanchalcone helps human hair cells grow and stimulates hair growth in mice by affecting certain cell signaling pathways.
89 citations
,
January 2009 in “Advances in Clinical Chemistry” Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.
124 citations
,
October 2019 in “Frontiers in Immunology” Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
90 citations
,
February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Interleukin-1 increases keratin K6 production in skin cells.
24 citations
,
March 2019 in “Life sciences” Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.
3 citations
,
January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
6 citations
,
February 2015 in “Anais Brasileiros de Dermatologia” Patients with mycosis fungoides have a higher risk of heart disease.
158 citations
,
August 2011 in “Reviews in endocrine and metabolic disorders” Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.
14 citations
,
October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
1 citations
,
March 2004 in “Journal of The European Academy of Dermatology and Venereology” Hair loss improved with treatment and successful transplant.
105 citations
,
August 2010 in “Pharmacology & therapeutics” Formyl-peptide receptor agonists could be new anti-inflammatory drugs.