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Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.

Myo-inositol may be more effective than metformin for inducing ovulation in women with PCOS.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Certain gene variations in AKT2 are more common in women with PCOS and are linked to higher levels of specific hormones and symptoms.

Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.

Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.

STK11 gene polymorphism does not predict metformin response in PCOS.

Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

Weight loss and metformin don't significantly change vaspin levels in women with PCOS.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Citrullus colocynthis has pain-relieving, anti-inflammatory, antidiabetic, and hair growth benefits, but can cause side effects like colic and diarrhea.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.