Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review explores enzyme inhibitors from gorgonians and soft corals and highlights their potential industrial and biomedical applications, but it reports no new experimental results.

In this study, cepharanthine showed potent antiviral effects against tick-borne encephalitis virus in vitro by reducing viral replication and inflammation in human lung and neuroblastoma cells.

This study found that ethanol extract of fragrant pandanus leaves inhibited the growth of the dandruff-causing fungus Pityrosporum ovale, with higher concentrations showing greater inhibitory effects.

This review discusses the unique pharmacokinetic limitations of terbinafine in children with tinea capitis and reports no new clinical results, highlighting the need for consideration of these factors in future studies.

This study explored new molecular structures as potential COVID-19 treatments, identifying a compound called Hit15 that inhibited viral infection in lab settings and reduced inflammation markers in human neutrophils, suggesting further development is warranted.

This study observed that tributyltin pollution induces imposex, reduces reproductive success, and leads to population decline in Ocinebrina aciculata, highlighting its sensitivity compared to other prosobranch species.

This study reported that a new sulfur paste formulation with added plant extract and propolis effectively treated scabies in rabbits by promoting rapid tissue regeneration, hair growth, and eliminating secondary infections, offering a more affordable and less irritating alternative to commercial treatments.

In this case report, a two-year-old girl with kerion type of tinea capitis successfully achieved clinical and mycologic cure with double pulse dose terbinafine and 2% ketoconazole shampoo over two months, with excellent tolerability and no side effects.

This study suggests that using particle-bound antiseptics may provide more effective and longer-lasting skin antisepsis compared to their non-particulate forms.

In this study on dogs, topical antimicrobial sprays with varying ingredient profiles showed different levels of S. pseudintermedius growth inhibition, maintaining activity for at least 10 days.

In this study, researchers isolated five new compounds from Monascus purpureus wmd2424 and found that four exhibited mild antifungal activity against several fungi.

This study found that methanolic extract of Eclipta alba leaves exhibited strong antibacterial effects against certain pathogens including methicillin-resistant Staphylococcus aureus, but it showed no activity against Mycobacterium tuberculosis, including drug-resistant strains.

This study found that the natural alkaloid cepharanthine effectively inhibited porcine epidemic diarrhea virus infection in newborn piglets.

In laboratory settings, this study found that finasteride repurposed as a quorum sensing inhibitor significantly reduced virulence factors of Pseudomonas aeruginosa, including biofilm formation by 45% and pyocyanin production by 49%, suggesting potential for treating infections.

This study found that the plant Clausena anisata exhibited promising antimicrobial, antioxidant, and anti-inflammatory activities against acne-causing bacteria and inflammation, suggesting its potential as a candidate for further anti-acne treatment research.

This study found that ethyl acetate extract from mangosteen pericarp exhibited the strongest antibacterial effect against Propionibacterium acnes compared to other extraction solvents.

This study identified natural compounds from Iris plants that showed potential as inhibitors of urease and carbonic anhydrase-II enzymes, suggesting their possible use in treating related disorders.

This study found that ointments containing indomethacin and its calcium salt showed potent anti-inflammatory effects on rat paw edema and arthritis with minimal skin irritation, suggesting potential for clinical use.

In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.

In this study, baicalin, a component of Baikal skullcap, was found to inhibit necroptosis in a cellular model of toxic epidermal necrolysis, suggesting it may be effective against severe drug-induced skin eruptions.

This study found that alkaloids isolated from Cucumis metuliferus fruit pulp demonstrated antiviral activity against IBDV in chicken embryo fibroblast cells and NDV in 10-day-old embryonated chicken eggs, while being non-cytotoxic.

In laboratory tests and mouse models, this study found that the novel IPC analog SIG-1451 may offer potent anti-inflammatory effects for treating allergic skin inflammation, potentially outperforming some current therapies in specific inflammatory phases.

In this study, the researchers developed and evaluated eco-friendly poly-herbal soap strips using plant extracts from Lantana camara, Moringa Oleifera, and Corn silk, finding that the strips exhibited superior physicochemical properties and significant anti-fungal activity compared to conventional anti-fungal soaps.

This systematic review highlights the diverse uses and bioactivities of Impatiens plants, particularly their antimicrobial, cytotoxic, anti-inflammatory, anti-anaphylactic, and antioxidant properties, while noting the need for more research to validate their ethnobotanical applications and isolate major bioactive compounds.

In this study, researchers reported that compounds from Bruguiera gymnorhiza leaves showed anti-inflammatory potential in in silico analyses, with favorable drug properties and specific binding to the IKKβ receptor, suggesting possible development into anti-inflammatory drugs.

In this study, zinc chloride was found to be severely irritant to the skin in rabbit, guinea-pig, and mouse models, while zinc oxide, zinc sulphate, zinc pyrithione, and zinc undecylenate showed minimal to no irritancy.

This study suggests that sericin microneedles with antibacterial and directional traction functionalities may enhance infected wound healing by improving skin repair and inhibiting bacterial growth, indicating potential for clinical application.

This study found that a hair serum formulated with extracts of Murraya koenigii and Clitoria ternatea demonstrated strong antifungal activity and effective dandruff management, based on laboratory evaluations.