Residual Antibacterial Activity of Canine Hair Treated with Topical Antimicrobial Sprays Against Staphylococcus Pseudintermedius In Vitro

The study investigated the residual antibacterial activity of canine hair treated with four different topical antimicrobial sprays against Staphylococcus pseudintermedius. Twelve dogs with no dermatological disease were treated, and hair samples were collected and tested over 10 days. The results showed significant differences in bacterial growth inhibition, with spray B (2% miconazole nitrate, 2% chlorhexidine gluconate, TrizEDTA) producing the largest inhibition zones, followed by sprays D, C, and A. All sprays demonstrated residual activity for the entire 10-day period. The study concluded that the efficacy of antimicrobial sprays depends on the concentration and combination of active ingredients, which could be beneficial for treating canine pyoderma.