Secondary Metabolites with Antifungal Activities from Mangrove Derived Fungus Monascus Purpureus WMD2424
March 2023
in “
Marine Drugs
”
Studysummary In this study, researchers isolated five new compounds from Monascus purpureus wmd2424 and found that four exhibited mild antifungal activity against several fungi.
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The study explores the antifungal properties of secondary metabolites from the mangrove-derived fungus Monascus purpureus WMD2424, identifying five new compounds. These compounds were tested against four fungal strains, showing varying degrees of antifungal activity. Notably, compound 3 demonstrated significant inhibition against Candida albicans with a MIC of 32.87 μg/mL, although none matched the efficacy of the control antifungal agent, ketoconazole. The research underscores the potential of these metabolites for antifungal applications, suggesting further investigation to improve their effectiveness.
