Effect of Mangosteen Pericarp Extract on Propionibacterium Acnes
January 2013
in “
วารสารเภสัชศาสตร์อีสาน (Isan Journal of Pharmaceutical Sciences, IJPS)
”
New to Mangosteen? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that ethyl acetate extract from mangosteen pericarp exhibited the strongest antibacterial effect against Propionibacterium acnes compared to other extraction solvents.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study investigated the antibacterial activity of mangosteen (Garcinia mangostana L.) pericarp extracts against Propionibacterium acnes, a bacterium associated with acne. The pericarp was extracted using methanol, and the extracts were further partitioned with hexane, ethyl acetate, and water. The active compound α-mangostin was identified using thin-layer chromatography. Among the extracts, the ethyl acetate extract demonstrated the strongest antibacterial effect, with a minimum inhibitory concentration (MIC) of 0.63 µg/ml and a minimum bactericidal concentration (MBC) of 19.06 µg/ml. The study concluded that ethyl acetate extract of mangosteen pericarp was most effective in inhibiting P. acnes growth.
