Natural Bisbenzylisoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity

    Matthew Kruger, Robert Boney, Alexander J. Ordoobadi … Allison B. Coffin
    Studysummary In this study using zebrafish, four bisbenzylisoquinoline derivatives were found to protect hair cells from aminoglycoside-induced damage without reducing antibiotic efficacy, potentially leading to therapies for patients undergoing such treatments.
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    Research cited in this study 2

    1. LSD1 Is Required for Hair Cell Regeneration in Zebrafish Molecular Neurobiology · 2015
    2. Molecular Basis of Hair Cell Loss Cell & tissue research/Cell and tissue research · 2015