Lamprey Teeth Inspired Oriented Antibacterial Sericin Microneedles for Infected Wound Healing Improvement

    March 2022 in “ Nano Letters
    Yan Deng, Cheng Yang, Yuanyuan Zhu, Wenyu Liu, Heli Li, Liping Wang, Wei Chen, Zheng Wang, Lin Wang
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    TLDR The document explains how to make antibacterial microneedles inspired by lamprey teeth to help heal infected wounds.
    The document describes the process of creating Oriented Antibacterial Sericin Microneedles (OASM) inspired by lamprey teeth for the purpose of improving infected wound healing. The sericin was isolated from natural fibroin-deficient mutant silk cocoons and combined with zinc oxide nanoparticles. The mixture was then added into Polydimethylsiloxane (PDMS) molds, which were designed in Solidworks and printed with yellow resin. The process involved centrifugation and vacuuming. The study does not provide the number of trials or the results of the application of these microneedles, focusing instead on the preparation method.
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