November 2022 in “Orphanet Journal of Rare Diseases” Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.
July 2021 in “Plastic and reconstructive surgery. Global open” Verteporfin treatment in mice led to complete skin healing without scarring.
June 2020 in “Journal of cosmetic medicine” TriCell CD34+ cell-containing PRP therapy improves hair thickness and density in alopecia patients without side effects.
December 2018 in “Journal of Medicinal and Aromatic Plant Sciences” Some plants like Eclipta alba, Nardostachys jatamansi, and Rumex japonicus may help hair growth.
January 2023 in “Journal of Clinical and Diagnostic Research” Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.
August 2022 in “Precision Clinical Medicine” JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.
February 2021 in “International journal of regenerative medicine” A new method using fat tissue cells may help treat hair loss.
Combining PRP with a special lotion is more effective for hair loss than PRP alone.
400 citations,
January 2014 in “British Journal of Sports Medicine” The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.
214 citations,
September 2015 in “Stem Cells Translational Medicine” Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
169 citations,
February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
136 citations,
September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
136 citations,
July 2014 in “Proceedings of the National Academy of Sciences of the United States of America” FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
134 citations,
July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
132 citations,
June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
115 citations,
April 2010 in “Archives of Dermatology” Surgical face-lifts are more effective, but fractional radiofrequency is a good, less invasive alternative for treating skin laxity.
114 citations,
January 2016 in “Current topics in developmental biology/Current Topics in Developmental Biology” Frizzled receptors are essential for various body development processes and maintaining certain body functions.
105 citations,
April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
88 citations,
September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
86 citations,
August 2021 in “Polymers” Microneedles are effective for drug delivery, vaccinations, fluid extraction, and treating hair loss, with advancements in manufacturing like 3D printing.
81 citations,
January 2000 in “American journal of clinical dermatology” Various treatments can improve post-acne scars, but results vary.
74 citations,
November 2000 in “Archives of Dermatology” Salicylic acid can safely exfoliate and regenerate skin without causing inflammation.
71 citations,
January 2012 in “PloS one” The conclusion is that genetic differences affect how the cochlea heals after hair cell loss, which may challenge the creation of hearing loss treatments.
61 citations,
June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
55 citations,
October 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
55 citations,
May 2019 in “Journal of Endocrinology” Androgens are important for female fertility and could help in IVF treatment, but also play a role in causing PCOS.
48 citations,
January 2017 in “International Journal of Trichology” Microneedling with platelet-rich plasma and minoxidil improves hair growth more than just minoxidil in men with hair loss.
46 citations,
January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
46 citations,
May 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Significant progress was made in understanding PXE, but effective treatments are still needed.
45 citations,
April 2009 in “Journal of anatomy” Cat claws stay sharp by shedding their outer layer through microcracks formed during activities.