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In this study, researchers developed a multilayered gel bead culture model using a microgel-spotting device, successfully mimicking the early development of skin appendages and supporting in vitro hair follicle regeneration with structures resembling native hair follicles.

This study developed an in vitro artificial hair germ model using dermal papilla cells and skin keratinocytes to explore early stages of hair follicle regeneration.

This study introduces a new type of tissue micromodule, the micro tissue precursor (μTP), which can form complex 3D tissues, including lung stroma and skin models supporting hair viability.

This study found that C. japonicum flower extract significantly increased melanin content and cellular activity in human melanocytes and may improve follicular depigmentation and vitiligo through cAMP signaling.

This study found that nanostructured lipid carriers could serve as a promising vehicle for topical Acitretin delivery in psoriasis treatment, potentially reducing oral side effects and enhancing patient compliance.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

This study demonstrates that incorporating human neopapilla into reconstructed human skin can initiate hair follicle morphogenesis by stimulating epidermal invagination and maintaining follicle-inductive properties in vitro.

This study found that various reduced folates effectively penetrated an in vitro skin model, promoted cell proliferation and migration, and may enhance wound healing, suggesting potential for topical treatment in skin conditions.

This article argues that lineage labeling with genetic markers is the gold standard for identifying epithelial stem cells, contrary to the view that in vitro methods alone are sufficient.

This review examines preclinical studies on exosome therapy for hair loss and reports no new human clinical findings.

This research explored hair loss and regrowth, highlighting the use of animal models like mice and rats to better understand hair physiology, shedding cycles, and potential treatments, with implications for human application.

This review discusses the role of dermal cells in hair follicle regeneration and morphogenesis and highlights their potential therapeutic implications, but it reports no new empirical findings.

In this study, researchers successfully derived skin organoids from mouse pluripotent stem cells that spontaneously produce hair follicles, potentially aiding in hair growth research and in vitro drug testing.

This review explores the potential of small molecules to activate the Wnt/β-catenin signaling pathway in treating diseases and reports no new experimental findings.

This chapter reviews laboratory models used for studying alopecia therapies but provides no new experimental findings.

This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.

This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.

This review discusses the biology of hair follicle stem cells and highlights their potential for applications in regenerative medicine, drug, and gene delivery, but reports no new clinical results.

This review synthesizes current knowledge on eyelash hair follicles, highlighting gaps in understanding their biology and proposing future research directions; it reports no new experimental findings.

This study found that preserving hair micrografts in an enriched storage medium for five hours significantly increased their survival rate compared to those stored in saline.

This review discusses various approaches to treating alopecia, including drug therapy and hair transplantation, but reports no new research findings; the authors highlight the need for novel techniques like cell culturing.

This study describes two methods for isolating hair follicle stem cells from newborn Yangtze River Delta White Goats, highlighting differences in cell viability and marker protein expression between the methods.

This study outlines a method to isolate hair follicle stem cells from mouse skin using fluorescence activated cell-sorting for use in research models, but reports no experimental findings.

This article reviews skin regeneration and fibrosis, identifying key cellular and molecular players, and emphasizing the potential to manipulate the postwound environment to promote regeneration over fibrosis.

This review discusses techniques and models for assessing hair growth activity but reports no new clinical findings, emphasizing the need for standardization and improved animal models.

Mesenchymal cells can significantly boost human hair growth and longevity.

This study found that plucked hair follicles exhibited a higher growth rate than conventional one-hair micrografts in vitro, suggesting they may be a less invasive alternative for hair transplantation.

This study developed a three-dimensional model for studying hair follicle development, showing that immortalized dermal papilla cells retain certain differentiation activities and can induce tubule formation in vitro.

This study developed a method for expanding human dermal papilla cells in vitro while maintaining their ability to induce hair growth, advancing the potential for follicular cell implantation as a treatment for hair loss.

This review discusses the history and challenges of hair follicle regeneration using follicular fragments and dissociated cells, without presenting new clinical results.