155 citations
,
August 2003 in “Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution” Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.
18 citations
,
March 2003 in “PubMed” Hair loss in women can be due to abnormal hair growth cycles or damaged hair follicles, with the most common type being androgenetic alopecia; treatment varies by cause, and the psychological impact is significant.
229 citations
,
August 2002 in “Experimental Gerontology” AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.
47 citations
,
April 2001 in “Journal of Dermatological Science” 98 citations
,
November 1999 in “Dermatology Online Journal” IGF-1 can boost hair growth by promoting cell growth and preventing cell death.
114 citations
,
October 1996 in “Dermatologic clinics” Hair loss is mainly caused by hormones, autoimmune issues, and chemotherapy, and needs more research for treatments.
36 citations
,
September 1996 in “PubMed” 441 citations
,
May 1996 in “Journal of Cell Science” Keratin 19 helps identify skin stem cells, with its presence varying by body location, age, and culture stage.
26 citations
,
January 1994 in “McGraw-Hill eBooks” Many hair loss conditions can be treated.
12 citations
,
July 1993 in “In Vitro Cellular & Developmental Biology - Animal” The study investigated the maintenance of hair follicles in culture, focusing on the effects of minoxidil on whisker follicles. By culturing follicles at the air-liquid interface on a modified collagen matrix, researchers observed a 2.7-fold increase in hair growth and an anagen-like morphology compared to submerged cultures. Minoxidil and its analogs were found to stimulate cysteine incorporation and specifically preserve the follicular root sheath, as indicated by increased TIMP expression and sulfotransferase activity. This preservation was not observed with the pinacidil analog, suggesting a unique action of minoxidil on the root sheath. The study concluded that the air-liquid interface culture method was superior for maintaining follicle morphology and promoting hair growth.
385 citations
,
November 1990 in “Journal of Cell Science” Human hair follicles can grow in a lab setting.
54 citations
,
June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
