Melanogenesis-Promoting Effect of Cirsium Japonicum Flower Extract In Vitro and Ex Vivo
October 2021
in “
International Journal of Cosmetic Science
”
Cirsium japonicum flower extract melanogenesis human melanocytes 3D skin model ex vivo human hair follicles melanin tyrosinase activity eumelanin pheomelanin HPLC cAMP signaling pathway phosphorylated CRE-binding protein pCREB microphthalmia-associated transcription factor MITF follicular depigmentation vitiligo CFE melanin synthesis CREB hair follicles tyrosinase cAMP
Studysummary This study found that C. japonicum flower extract significantly increased melanin content and cellular activity in human melanocytes and may improve follicular depigmentation and vitiligo through cAMP signaling.
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