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Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.

Oral tofacitinib successfully treated total body hair loss in one patient.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

Chitosan-based dressings reduce inflammation and speed up skin wound healing.

Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.

Frontal fibrosing alopecia shows increased inflammation and JAK-STAT pathway activity without reduced hair proteins.

Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.

Ginsenoside Rg1 protects mouse skin from UVB damage and helps control inflammation.

Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.

Lithocholic acid helps hair growth and regeneration in alopecia by activating vitamin D receptors.

Higher levels of certain DNAs in blood may indicate hair follicle damage in alopecia areata patients.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

Immunomodulatory therapies are effective for treating cutaneous lymphoma, particularly in early stages.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

ILC1-like cells can cause alopecia areata by attacking hair follicles.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

New treatments for hair loss show promise but need more research to confirm safety and effectiveness.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

ILC1 cells contribute to hair loss in alopecia areata.

AIRE deficiency causes hair loss similar to alopecia areata in mice.

Argan press cake extract might help grow hair and protect hair cells from damage and inflammation.

Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.

Targeting and modifying the stem cell niche can improve regenerative therapies.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Alopecia areata may be treated by restoring hair follicle immune privilege and adjusting immune responses.

Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.