Effective Treatment of Alopecia Universalis with Oral Tofacitinib: A Case Report

In 2021, a case report documented the successful use of oral tofacitinib in treating alopecia universalis, a condition causing total body hair loss, in a 29-year-old female patient. The patient, who had alopecia totalis since 2015 and rheumatoid arthritis for a decade, experienced significant hair regrowth on her scalp, eyebrows, eyelashes, and entire body after 13 months of tofacitinib treatment. No side effects or relapses were reported. The report concluded that oral tofacitinib effectively treated alopecia universalis, but emphasized the need for further clinical trials with longer follow-ups to validate these findings.