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The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.

The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

Agaricus bisporus derived β-Glucan could be an effective cervical cancer treatment with antimicrobial and antioxidant properties.

LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Argan oil protects hair from oxidative damage and reduces protein loss.

Compound 4 is a promising treatment for hair loss with low toxicity.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

A new compound effectively inhibits human 5α-reductase 1.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Sebocytes play a key role in controlling androgen levels in human skin.

Both drugs lower DHT levels, with GI198745 being more effective.

Finasteride-loaded nanoparticles may help treat alopecia.

Tedisamil and glibenclamide affect cromakalim and minoxidil sulphate differently in rat aorta.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Umbilical cord-derived media is safe and effective for hair growth.

Finasteride helps hair growth and prostate issues but may cause sexual side effects and increase tumor risk.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Androgens, like testosterone, are crucial for early testicular descent in rats.