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![Gonads](/images/research/f87eba17-a0ed-4f86-8e9d-7b68f85bff8e/small/14316.jpg)
research Gonads
The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.
![Editors' Picks](/images/research/dadf8c2c-80aa-4964-9a2a-82e2885611c6/small/12855.jpg)
research Editors' Picks
Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.
![Histocompatibility and Long-Term Results of Follicular Unit-Like Wigs After Xenogeneic Hair Transplantation: An Experimental Study in Rabbits](/images/research/7544557a-0d7c-40d4-a521-6088e0cc8a4d/small/26171.jpg)
research Histocompatibility and Long-Term Results of Follicular Unit-Like Wigs After Xenogeneic Hair Transplantation: An Experimental Study in Rabbits
The wigs made from human hair and polypropylene were mostly well-tolerated and durable in rabbits, suggesting they could be a new option for people with extensive hair loss.
![The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report](/images/research/93322fb5-dc54-4707-b200-ca2eae38a4e5/small/14935.jpg)
research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
![Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline](/images/research/72746a3a-00db-4264-86e7-a04980366ba6/small/14451.jpg)
research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
![Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers](/images/research/18592881-c07d-41cc-b603-b131e21a554e/small/29324.jpg)
research Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
![Anticancer Drugs in Surface Waters](/images/research/80d1d63c-3865-4b73-b103-8c1a18985640/small/14709.jpg)
research Anticancer Drugs in Surface Waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
![Visually Scoring Hirsutism](/images/research/241ec756-f1ad-467d-8901-069d4c4c090a/small/32545.jpg)
research Visually Scoring Hirsutism
The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.
![SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder](/images/research/9b9d6ab8-c7ba-45b1-9419-1bb4c58fc136/small/20353.jpg)
research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder
Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.
![Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline](/images/research/2254a31a-f7c4-4952-9e76-5180158f50f3/small/20990.jpg)
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
![JAK Inhibitors: New Players in the Field of Immune-Mediated Diseases Beyond Rheumatoid Arthritis](/images/research/ca9b23f7-49e8-45d8-94b3-89ea442ed497/small/31403.jpg)
research JAK Inhibitors: New Players in the Field of Immune-Mediated Diseases Beyond Rheumatoid Arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
![Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men](/images/research/531dcd56-bd99-4851-9576-02e89dc41e25/small/3089.jpg)
research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men
Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
![Targeting the Janus Kinase Family in Autoimmune Skin Diseases](/images/research/268f8ecd-6b18-432d-9808-5b7ee0cb86a9/small/17604.jpg)
research Targeting the Janus Kinase Family in Autoimmune Skin Diseases
Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.
![A Review of Diagnosis and Treatment of Acne in Adult Female Patients](/images/research/b08990d1-4e89-4c65-84c4-b0b81132db99/small/17916.jpg)
research A Review of Diagnosis and Treatment of Acne in Adult Female Patients
Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.
![Genetic Basis of Skin Appendage Development](/images/research/ef7af60b-9dab-420c-b54a-960777778b64/small/35666.jpg)
research Genetic Basis of Skin Appendage Development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
![Baiting Proteins with C60](/images/research/1e46ccd8-1642-41ff-b712-f0f914e3fb29/small/14846.jpg)
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
![Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form](/images/research/f3ac5424-c101-4e27-8b74-e6c280e57d75/small/29408.jpg)
research Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form
A genetic change in the EDAR gene causes the unique hair traits found in East Asians.
![Hormones and the Pilosebaceous Unit](/images/research/70cb22ba-c982-4fa9-ab32-9779d2bef757/small/30930.jpg)
research Hormones and the Pilosebaceous Unit
Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
![Nutraceuticals: A Review](/images/research/40f56b73-4409-48b0-8110-f6852154e605/small/17995.jpg)
research Nutraceuticals: A Review
Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
![Androgenetic Alopecia: An Update](/images/research/f8e7cc64-3b83-4af9-b817-31bf259d4487/small/3353.jpg)
research Androgenetic Alopecia: An Update
Minoxidil and finasteride effectively treat hair loss.
![Safety of Testosterone Treatment in Postmenopausal Women](/images/research/b514d62b-f086-4f49-a696-c3e3dc36de23/small/15170.jpg)
research Safety of Testosterone Treatment in Postmenopausal Women
Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
![Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases](/images/research/5ba83402-9104-46cd-9957-6cb4d8c385a0/small/17947.jpg)
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
![What Causes Hidradenitis Suppurativa?—15 Years After](/images/research/796638a2-c82a-4f8d-83c9-370712b989e3/small/17352.jpg)
research What Causes Hidradenitis Suppurativa?—15 Years After
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
![Clinical and Biological Impact of the Exposome on the Skin](/images/research/330375bc-1426-4cc2-9fee-2bfa0ecd24b6/small/17438.jpg)
research Clinical and Biological Impact of the Exposome on the Skin
Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.
![Adipocytes in Skin Health and Disease](/images/research/a059828e-0e61-4c11-a118-28dd13684aa9/small/14354.jpg)
research Adipocytes in Skin Health and Disease
Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
![The SAHA Syndrome: Overview and Classification](/images/research/2e9523f5-7079-484b-9229-23c1fc65afbe/small/25198.jpg)
research The SAHA Syndrome: Overview and Classification
SAHA syndrome is a condition in women involving skin and hair issues, often related to hormonal imbalances, and is treated based on the underlying cause.
![Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome](/images/research/dc534140-beb9-4091-8316-51d9bd25d8a0/small/15205.jpg)
research Ovarian Leukocyte Distribution and Cytokine/Chemokine mRNA Expression in Follicular Fluid Cells in Women with Polycystic Ovary Syndrome
Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
![Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas](/images/research/4e300b8a-58df-48a7-8308-baf37e11953e/small/25077.jpg)
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
![A Current Review of the Cutaneous Manifestations of Renal Disease](/images/research/bb4f5a65-fbf9-434a-ba33-2872af742708/small/29884.jpg)
research A Current Review of the Cutaneous Manifestations of Renal Disease
Skin problems are very common in people with end-stage kidney disease.