Ursolic Acid Reduces Prostate Size and Dihydrotestosterone Level in a Rat Model of Benign Prostatic Hyperplasia

    January 2012 in “ Food and chemical toxicology ”
    In–Sik Shin, Mee-Young Lee, Da-Young Jung … Hyeun‐Kyoo Shin
    Studysummary In a testosterone-induced BPH rat model, this study found that ursolic acid treatment significantly reduced prostate weight and hormone levels, suggesting it may inhibit BPH development.
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    Research cited in this study 3

    1. Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders Current Pharmaceutical Design · 2011
    2. Potency of a Novel Saw Palmetto Ethanol Extract, SPET-085, for Inhibition of 5α-Reductase II Advances in Therapy · 2010
    3. Dihydrotestosterone And The Prostate: The Scientific Rationale For 5α-Reductase Inhibitors In The Treatment Of Benign Prostatic Hyperplasia ˜The œJournal of urology/˜The œjournal of urology · 2004