April 2019 in “Journal of the Endocrine Society” This case report highlighted rapid virilization in a woman with adrenocortical carcinoma, stressing the importance of androgen evaluation to suspect underlying ovarian or adrenal tumors.
September 2024 in “Medicine theory and practice” In a clinical case study, researchers identified adrenocortical adenoma as the cause of hyperandrogenism syndrome in a preschool-aged girl, following a comprehensive diagnostic process and successful surgical intervention to remove the tumor, leading to positive clinical improvements.
1 citations
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July 2022 in “Case reports in endocrinology” This case report concludes that a combination of physical examination, hormonal evaluation, and imaging studies is crucial for identifying malignant adrenal masses, with radical excision and adjuvant therapy improving patient outcomes.
March 2023 in “Bagcılar medical bulletin” This case report highlights a rare diagnosis of an androgen-secreting adrenal tumor in a patient with hyperandrogenism and virilization symptoms, emphasizing the role of gynecologists in early detection.
30 citations
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January 2001 in “Journal of the American Veterinary Medical Association” This study found that adrenal sex hormone levels were elevated in neutered dogs with hypercortisolemia, except for testosterone, highlighting the importance of ruling out hypercortisolemia when diagnosing adrenal hyperplasia syndrome.
May 2021 in “Journal of the Endocrine Society” This case report highlights the importance of timely biochemical and radiographic evaluation of adrenal masses, as illustrated by a rapidly progressing aggressive adrenal cortical carcinoma.
77 citations
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September 1983 in “Acta Paediatrica” In this study, administering dexamethasone rapidly normalized elevated steroid levels in girls with premature adrenarche.
2 citations
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December 2016 in “PubMed” This paper reviews adrenocortical carcinoma, discussing its prevalence, symptoms, diagnosis, and treatment options, but reports no new clinical results.
April 2014 in “Acta Medica Colombiana” This study presents a 63-year-old man with uncontrolled hypertension and facial hair who was diagnosed with adrenocortical adenoma, and whose blood pressure improved post-surgery.
5 citations
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December 2004 in “Dermatology” This review describes two cases of young women with primary amenorrhea and hyperandrogenemia, suggesting that adrenal tumors should be considered in patients with significantly elevated circulating testosterone levels.
7 citations
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January 2013 in “Hormone Research in Paediatrics” This case report describes an adult female with congenital adrenal hyperplasia who developed secondary amenorrhea and hair loss due to androgen overproduction from ovarian adrenal rests, detectable only after pelvic venous sampling, and normalizing after unilateral oophorectomy.
10 citations
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December 1992 in “PubMed” This report of three cases found that diagnosing hypercortisolism during pregnancy can be challenging, but early detection using unbound steroid levels and MRI could prevent severe complications.
November 2022 in “Journal of the Endocrine Society” This case study reports a rare instance of a virilizing androgen-only secreting adrenal cortical adenoma in a 13-year-old, with symptom resolution after surgical removal.
41 citations
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September 1951 in “Annals of Internal Medicine” This review discusses the interrelationship between the anterior pituitary's adrenocorticotropic hormone (ACTH) and the adrenal cortex, but reports no new experimental findings.
2 citations
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November 2011 in “InTech eBooks” This article reviews the types and characteristics of adrenal cortex tumors, including their hormone secretion and detection as incidental findings, but presents no new research results.
June 2025 in “V F Snegirev Archives of Obstetrics and Gynecology” In this case study, a six-year-old girl was diagnosed with isolated adrenarche, linked to premature adrenal maturation, with increased dehydroepiandrosterone sulfate and axillary and pubic hair growth, and will require long-term monitoring due to increased risks of conditions like polycystic ovary syndrome and cardiovascular diseases.
October 2025 in “Journal of the Endocrine Society” This case report describes a 36-year-old female patient with panhypopituitarism, experiencing severe adrenal insufficiency and thyroid hormone deficiency, which led to electrolyte imbalance, QT interval prolongation, and ventricular tachycardia; treatment stabilized her condition, underscoring the importance of hormonal evaluation in arrhythmia assessment.
February 2025 in “Skin Appendage Disorders” In this case report, a 62-year-old postmenopausal woman with hyperandrogenism exhibited male-pattern alopecia and hirsutism, which improved after bilateral adrenal adenomas were removed, underscoring the need for investigation of androgen-producing tumors in similar cases.
11 citations
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January 2013 in “Indian Journal of Endocrinology and Metabolism” This case study describes an extremely rare instance of androgen-secreting adrenocortical carcinoma in a patient with non-classical congenital adrenal hyperplasia.
16 citations
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September 2009 in “Schweizer Archiv für Tierheilkunde” This case report describes an 8-year-old Russian Blue cat with bilateral adrenal carcinomas secreting high levels of progesterone, showing symptoms similar to hypercortisolism.
July 2019 in “Journal of the ASEAN Federation of Endocrine Societies” This case report describes a young woman with an adrenal oncocytic tumor of uncertain malignant potential, highlighting the need for ongoing surveillance due to possible malignancy.
55 citations
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August 2008 in “Reviews in endocrine and metabolic disorders” This review discusses clinical, hormonal, and genetic aspects of nonclassic adrenal hyperplasia and reports no new findings; the condition is highlighted as a potential cause of premature adrenarche and other symptoms in young people.
In this case report, a 10-year-old girl with an adrenal adenoma experienced symptoms like hirsutism and clitoromegaly; after surgical removal of the tumor, her symptoms and biochemical abnormalities resolved over several months.
May 2016 in “Endocrine Abstracts” The removal of the adrenal tumor improved the patient's symptoms and reduced androgen levels, indicating successful surgery.
1 citations
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December 2019 in “Medical Journal of Dr D Y Patil Vidyapeeth” This case report details a 26-year-old woman with a rare large functional adrenal myelolipoma, characterized by elevated hormone levels and requiring surgical intervention.
May 2025 in “Journal of the ASEAN Federation of Endocrine Societies” This case study highlights a testosterone- and cortisol-secreting adrenal oncocytic neoplasm in an 18-year-old woman, illustrating the role of surgical excision in resolving hyperandrogenism and restoring menstruation.
14 citations
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January 2000 in “Endocrine Journal” This case report documents a 57-year-old woman with a renin-producing adrenocortical carcinoma, revealing metastasis in the neck and providing insights into treatment effectiveness with trilostane and mitotane.
April 2019 in “Journal of the Endocrine Society” This report describes an exceptionally rare adrenal neoplasm in a post-menopausal woman that exclusively secreted DHEA-S, with significant serum level reduction following adrenalectomy.
22 citations
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February 2010 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” This article reviews the evidence regarding the role of sex hormones in occult hyperadrenocorticism and reports no new findings, highlighting the unproven nature of their involvement.
6 citations
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January 2013 This chapter reviews hyperadrenocorticism in ferrets, covering its causes, symptoms, diagnosis, and treatment options, but reports no new research findings.