Adrenocortical Adenoma as a Cause of Hyperandrogenism Syndrome in a Girl: The Path to Diagnosis
September 2024
in “
Medicine theory and practice
”
TLDR A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.
A 4-year-old girl presented with symptoms of hyperandrogenism, including rapid weight gain, acne, and clitoral hypertrophy. Laboratory tests showed elevated levels of testosterone, androstenedione, 17-OH progesterone, and DHEA sulfate, along with disrupted cortisol rhythms. Ultrasound and subsequent MSCT identified a cystic-solid mass in the left adrenal gland. Surgical removal and histological examination confirmed an adrenocortical adenoma. The diagnostic process and treatment spanned 20 days, highlighting the importance of comprehensive biochemical, hormonal, and instrumental evaluations in diagnosing hormone-producing adrenal tumors in young girls.
