Adrenocortical Adenoma as a Cause of Hyperandrogenism Syndrome in a Girl: The Path to Diagnosis
September 2024
in “
Medicine theory and practice
”
TLDR A young girl's hyperandrogenism was caused by an adrenocortical adenoma, diagnosed and treated through detailed evaluations.
A 4-year-old girl presented with significant weight gain, acne, pubic hair growth, and clitoral hypertrophy, indicative of hyperandrogenism. Laboratory tests showed elevated levels of testosterone, androstenedione, 17-OH-progesterone, and DHEA-sulfate, along with disrupted cortisol rhythms. Ultrasound and MSCT identified a cystic-solid mass in the left adrenal gland. Surgical removal and histological examination confirmed an adrenocortical adenoma. Postoperative outcomes showed significant clinical and laboratory improvement.
